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Determination of Flavonoids in Selected Species and Their Anti-Collagenase and Antioxidant Potential. | LitMetric
A new 5,7-dihydroxy-3'-methoxy-4'-acetoxyflavone-8---d-arabinopyranoside-2″--(4‴-acetoxy)-glucoside () and three known flavone -glycosides-5,7,3',4'-tetrahydroxyflavone-6--xyloside-8---d-glucoside (lucenin-1) (), 5,7,3'-trihydroxyflavone-6--glucoside-8---d-glucoside (vicenin-2) (), and 5,7,4'-trihydroxy-3'-methoxyflavone-6---d-glucopyranoside-8---arabinopyranoside (chrysoeriol-6---d-glucopyranoside-8---arabinopyranoside) ()-were isolated from aerial parts of L. (Caryophyllaceae). Their structures were determined through the use of comprehensive spectroscopic and spectrometric methods, and a method for the quantification of the major constituents of and L. was developed. Furthermore, the anti-collagenase and antioxidant activities of all isolated compounds obtained from extracts and fractions from both species were evaluated. The highest percentage of collagenase inhibition (at 400 µg/mL) was distinguished for methanolic extracts (22.06%, 32.04%) and ethyl acetate fractions (16.59%, 14.40%) from and . Compounds - displayed moderate inhibitory activity, with IC values ranging from 39.59-73.86 µM.
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