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Background: Subclinical hypothyroidism (SCH) is synonymous with thyroid failure (a milder form). It is a condition characterized by normal laboratory ranges of serum FT4 and FT3 levels, but serum thyroid stimulating hormone (TSH) levels are slightly increased above the normal range.

Objective: The leading aims and objectives of the study were: (1) establishing a correlation between the presence of modifiable risk factors of ischemic heart disease in subjects with SCH.

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Article Synopsis
  • * Results showed that in individuals with sufficient vitamin A, higher AIP was linked to increased total triiodothyronine (TT3), while those severely deficient in vitamin A had different responses in hormone levels and a heightened risk of subclinical hypothyroidism with elevated AIP.
  • * The risk linked to vitamin A deficiency and AIP was significantly greater in women and older adults, indicating a demographic difference in vulnerability to these health issues.
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Background: The impact of thyroid function on the risk of various types of dementia, including Alzheimer's disease (AD) and vascular dementia (VD), remains unclear. This meta-analysis investigates the association between thyroid dysfunction and the risk of these dementia types, aiming to inform strategies for dementia prevention.

Methods: A comprehensive search was conducted in PubMed, Embase, and the Cochrane Library for studies published up to February 2023, focusing on the risk of thyroid dysfunction in dementia.

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Aortic thrombosis and acute kidney injury due to atherosclerosis in a dog.

J Am Vet Med Assoc

August 2024

1Section of Emergency and Critical Care, Veterinary Teaching Hospital, Catholic University of Valencia, Valencia, Spain.

Objective: Atherosclerosis is a chronic lipid-driven inflammatory disease of the arterial wall. Due to its cardiovascular ischemic complications, it is one of the most common causes of death in people. However, atherosclerosis is seldomly reported in dogs.

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Introduction: Coronary artery bypass grafting (CABG) is a surgical procedure that restores blood flow to heart muscle by bypassing the blocked or narrowed coronary arteries. On the other hand, subclinical hypothyroidism (SCH) is characterized by an elevated serum concentration of thyroid stimulating hormone with normal levels of serum free thyroxine. With limited research into the impact of SCH on postoperative CABG outcomes, this systematic review and meta-analysis was performed.

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