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Perspectives and Practices of Healthcare Leaders in Supporting Healthcare Worker Well-Being: A Reality Check.
J Healthc Leadersh
January 2025
Department of Anaesthesiology, University Medical Centre Groningen, Groningen, the Netherlands.
Introduction: The well-being of healthcare workers (HCWs) is a critical concern. While healthcare leaders can play a crucial role in influencing employees' well-being, it remains unclear how leaders are leveraging this influence. This study aims to unravel the current perspectives and practices of healthcare leaders in supporting HCW well-being.
View Article and Find Full Text PDFDon't pretend COVID-19 didn't happen.
Science
January 2025
Maria D. Van Kerkhove is a director at the World Health Organization, leading the Department of Epidemic and Pandemic Threat Management, and serves as the COVID-19 Technical Lead and Emergency Manager in the Health Emergencies Programme, Geneva, Switzerland.
Just over 5 years ago, on New Year's Eve 2019, the World Health Organization (WHO) became aware of the first cases of pneumonia of unknown etiology in Wuhan, China. A massive global infectious disease storm was already brewing-one that would shut down the world, with profound economic, social, and political impacts that still reverberate today. It's understandable that governments and individuals may want to forget that the COVID-19 pandemic ever happened, but such collective amnesia prevents humanity from being ready for the next pandemic.
View Article and Find Full Text PDFScience tells us that portable air filters reduce infection risk. It's time for public health authorities to make this clear.
J Infect Public Health
January 2025
Dalla Lana School of Public Health, University of Toronto, 155 College St., Toronto, Ontario M5T 3M7, Canada; Department of Civil & Mineral Engineering, 35 St. George St, Toronto, Ontario M5S 1A4, Canada.
Throughout the COVID-19 pandemic, Canadian public health advisors and politicians have shared mixed messages about the utility of portable air filters (PAFs) for mitigating the transmission of airborne infectious diseases. Some public health advisors and decision-makers have also suggested that PAFs are cumbersome or require expert advice. We take this opportunity to review evidence and address myths about PAFs.
View Article and Find Full Text PDFComparing the efficacy and safety of extended vs standard dosing of ocrelizumab in MS: A systemic review and meta-analysis.
Mult Scler Relat Disord
January 2025
Dow University of Health Sciences, Karachi, Pakistan.
Introduction: Multiple Sclerosis (MS) is a challenging autoimmune disease that disrupts the central nervous system, leading to a range of symptoms. Ocrelizumab, a treatment commonly used for MS, targets B cells to help manage the disease. While the standard-interval dosing (SID) is effective, the COVID-19 pandemic raised concerns about safety, particularly around immune responses.
View Article and Find Full Text PDFIFN- signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice.
bioRxiv
January 2025
Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Neurotropic viruses are a major public health concern as they can cause encephalitis and other severe brain diseases. Many of these viruses, including flaviviruses, herpesviruses, rhabdoviruses and alphaviruses enter the brain through the olfactory neuroepithelium (ONE) in the olfactory bulbs (OB). Due to the low percentage of encephalitis that occurs following these infections, it's thought that the OBs have specialized innate immune responses to eliminate viruses.
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