Driving under the influence of alcohol has been shown to increase the risk of involvement in road traffic collisions (RTCs) however, less is known about the effects of illicit drugs, and a clear correlation between drug concentrations and RTC risk is still debated. The goal of this narrative review is to assess the current literature regarding the most detected psychoactive drugs in RTC (ethanol, amphetamines, cannabis, opioids and cocaine), in relation to driving performance. Evidence on impaired driving due to psychoactive substances, forensic issues relating to the assessment of the impact of drugs, blood cut-off values proposed to date as well as scientific basis for proposed legislative limits are discussed. At present there is no unequivocal evidence demonstrating a clear dose/concentration dependent impairment in many substances. Per se and zero tolerance approaches seem to have negative effect on drugged driving fatalities. However, the weight of these approaches needs further investigation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938866 | PMC |
| http://dx.doi.org/10.1016/j.fsisyn.2022.100224 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spindle-Shaped Ni-Fe-Layered Double Hydroxide: Effect of Etching Time on Flexible Energy Storage.
Small
January 2025
Nanotechnology and Bio-Engineering Research Group, Atlantic Technological University, ATU Sligo, Ash Lane, Sligo, F91 YW50, Ireland.
The rising demand for efficient energy storage in flexible electronics is driving the search for materials that are well-suited for the fabrication of these devices. Layered Double Hydroxides (LDHs) stand out as a remarkable material with a layered structure that embodies exceptional electrochemical properties. In this study, both double-shelled and single-shelled NiFe-Layered Double Hydroxide (LDH) particles are prepared using spindle-shaped MIL-101(Fe) as the template.
View Article and Find Full Text PDFIntegrated Decision and Motion Planning for Highways with Multiple Objects Using a Naturalistic Driving Study.
Sensors (Basel)
December 2024
Western Science City Intelligent and Connected Vehicle Innovation Center (Chongqing) Co., Ltd., Chongqing 400015, China.
With the rise in the intelligence levels of automated vehicles, increasing numbers of modules of automated driving systems are being combined to achieve better performance and adaptability by reducing information loss. In this study, an integrated decision and motion planning system is designed for multi-object highways. A two-layer structure is presented to decouple the influence of the traffic environment and the dynamic control of ego vehicles using the cognitive safety area, the size of which is determined by naturalistic driving behavior.
View Article and Find Full Text PDFThe Effect of Postoperative Sepsis on 1-Year Mortality and Cancer Recurrence Following Transhiatal Esophagectomy for Esophageal-Gastric Junction Adenocarcinomas: A Retrospective Observational Study.
Cancers (Basel)
January 2025
Department of Anesthesiology and Critical Care, Paoli-Calmettes Institute, 13009 Marseille, France.
Introduction: Transhiatal esophagectomy (THE) is used for specific gastroesophageal junction adenocarcinomas. THE is a high-risk surgical procedure. We aimed to assess the impact of postoperative sepsis (sepsis or septic shock) on the 1-year mortality after THE and to determine the risk factors associated with these outcomes.
View Article and Find Full Text PDFEffect of Gut Dysbiosis on Onset of GI Cancers.
Cancers (Basel)
December 2024
Division of Hematology and Oncology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Dysbiosis in the gut microbiota plays a significant role in GI cancer development by influencing immune function and disrupting metabolic functions. Dysbiosis can drive carcinogenesis through pathways like immune dysregulation and the release of carcinogenic metabolites, and altered metabolism, genetic instability, and pro-inflammatory signalling, contributing to GI cancer initiation and progression. infection and genotoxins released from dysbiosis, lifestyle and dietary habits are other factors that contribute to GI cancer development.
View Article and Find Full Text PDFThe Properties of Damaged Starch Granules: The Relationship Between Granule Structure and Water-Starch Polymer Interactions.
Foods
December 2024
Instituto de Ciencia y Tecnología de los Alimentos Córdoba (ICYTAC-CONICET), Universidad Nacional de Córdoba, Av. Filloy S/N, Ciudad Universitaria, Córdoba CP 5000, Argentina.
The morphology of wheat starch granules with different damaged starch (DS) content was analyzed using a particle size analyzer and scanning electron microscopy (SEM); the granular structure was studied using FT-IR spectroscopy and X-ray diffraction (XRD); and the granule-water interaction was evaluated by thermogravimetric analysis (TGA) and dynamic vapor sorption (DVS). The increase in the level of DS shifted the population of B-type granules towards larger particle diameters and shifted the population of A-type granules towards smaller particle diameters. The appearance of the surface of the starch-damaged granules was rough and flaky (SEM images).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!