Venovenous extra corporeal life support in an infant with foreign body aspiration: A case report.

Respir Med Case Rep

Department of Pediatric Critical Care, Critical Care Center, King Fahad Medical City, Riyadh, Saudi Arabia.

Published: March 2022

Background: Foreign body aspiration (FBA) is a life-threatening emergency and a common cause of morbidity and morbidity in children. FBA can lead to rapidly progressive respiratory failure. Stabilizing patients after FBA for bronchoscopic removal of the aspirated object can be complex and may necessitate advanced support such as high-frequency oscillatory ventilation (HFOV) or extracorporeal membrane oxygenation (ECMO). This case report presents the feasibility of using ultrasound (US) in percutaneous catheterization in infants and the benefit of using venovenous ECMO (VV-ECMO) as rescue therapy in FBA.

Case Summary: A 10-month-old girl accidently aspirated a metallic piece that was dislodged further to the right main bronchus after failed trials to remove it. She was intubated and mechanically ventilated, complicated by milk aspiration and bilateral pneumothoraces secondary to high-pressure lung ventilation. She had refractory mixed respiratory failure despite high settings of HFOV and inhaled nitric oxide. Venovenous ECMO (VV-ECMO) was initiated for stabilization and a bridge for bronchoscopic foreign body removal and awaiting lung recovery. She was weaned off ECMO after 166 hours. The patient was extubated after a few days and discharged home 28 days after admission without clinical evidence of neurological or respiratory complications. ECMO has been described in the literature as rescue therapy for FBA resulting in respiratory failure. However, ECMO cannulation in children under these circumstances is challenging because of vessel size restrictions. Two-vessel cannulation or dual-lumen cannulation are available options via open cut-down or percutaneous cannulation techniques, depending on the general expertise. The use of vascular ultrasound to assess vessel size is a helpful tool for cannulating infants.

Conclusion: VV-ECMO support is expanding for respiratory failure in pediatric patients. Percutaneous cannulation in infants and children for VV-ECMO is safe and feasible.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938911PMC
http://dx.doi.org/10.1016/j.rmcr.2022.101636DOI Listing

Publication Analysis

Top Keywords

respiratory failure
16
foreign body
12
body aspiration
8
case report
8
venovenous ecmo
8
ecmo vv-ecmo
8
rescue therapy
8
vessel size
8
percutaneous cannulation
8
ecmo
6

Similar Publications

Background: During the COVID-19 pandemic, severe respiratory failure is a life-threatening condition, and life-saving tracheal intubation is a high-risk aerosol- and droplet-generating procedure. It is crucial to protect healthcare workers without compromising patient safety during intubation. The use of personal protective equipment (PPE) and different types of laryngoscopes are measures to reduce the risk of infectious transmission that might impact the intubation process.

View Article and Find Full Text PDF

This case report describes a geriatric male patient with myasthenia gravis (MG) secondary to giant thymoma, presenting with progressive muscle weakness and ptosis. The diagnosis of MG was confirmed through pathology, imaging, and laboratory evaluations. Considering the significant surgical risks associated with the giant thymoma, adjuvant chemotherapy was initiated.

View Article and Find Full Text PDF

Acute respiratory distress syndrome (ARDS) incidence following minimally invasive cardiac surgery (MICS) is rare. We report a case of acute respiratory failure following cardiac surgery that was diagnosed as ARDS. A 77-year-old female patient diagnosed with aortic valve stenosis underwent aortic valve replacement via a right thoracotomy.

View Article and Find Full Text PDF

A Breathtaking Case of Chemotherapy-Induced Pneumonitis.

Cureus

February 2025

Internal Medicine, Henry Ford Health System - Warren, Warren, USA.

Medication-induced pulmonary toxicity is a rare adverse event that may occur with many chemotherapeutic agents, including etoposide. This agent has been found to cause various toxicities, including anaphylaxis, angioedema, hypotension, and pneumonitis. Etoposide is used in chemotherapy regimens for multiple cancers, including germ-cell tumors.

View Article and Find Full Text PDF

Low-Level Viremia Impairs Efficacy of Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma.

Liver Int

April 2025

State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.

Background And Aims: The impact of low-level viremia(LLV) on the efficacy of immune checkpoint inhibitors (ICIs) in unresectable hepatocellular carcinoma(uHCC) patients remains unclear. This study aims to investigate the effect of LLV on the outcomes of ICIs-based therapy in patients with uHCC.

Methods: In this multicenter retrospective study, we included patients with uHCC who received ICIs-based therapy at four centres between January 2019 and December 2022.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!