The fuel booster pump is one of the most vulnerable physical assets in an operating engine due to the harsh environmental and operational conditions. However, because of its high structural complexity and extreme operational conditions, the reliability design of the fuel booster pump becomes especially difficult, particularly by means of experiments. Thus, to overcome such a problem, advanced simulation techniques have become adequate solutions for the reliability assessment and analysis of a fuel booster pump at the design stage. In this paper, by considering the effects of the uncertainties of multiple design parameters, fatigue life distributions of the four key components (which are the sealing bolt, spline shaft, graphite ring, and inducer, respectively) in a fuel booster pump were first predicted by PoF-based reliability simulations. Then, through further sensitivity analysis on each key component, the design parameters most sensitive to the component mean fatigue life were detected from a total of 25 candidate parameters. These parameters include the "nominal diameter" and "preload" for the sealing bolt, "major and minor diameters of the small spline" for the spline shaft, "inside diameter" for the graphite ring, and "fuel pressure on the blade front surface" for the inducer, respectively. These sensitivity results were found to be in good agreement with the results from the qualitative cause analysis on each key component.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954254 | PMC |
http://dx.doi.org/10.3390/ma15061989 | DOI Listing |
Heliyon
September 2024
Delft University of Technology, Faculty of EEMCS, Delft, the Netherlands.
An economical approach for incorporating Battery Energy Storage Systems (BESS) onto DP-2 vessels is presented in this research. The paper deals with developing a Battery Optimization for Optimal Sizing and Throughput Energy Regulation (BOOSTER) framework for putting research findings into practice by optimizing battery size, technology choice and power generation scheduling while considering battery degradation. Twelve battery sizes are analyzed based on three key performance metrics: return on investment, payback period, and years of profitability.
View Article and Find Full Text PDFBiotechnol Biofuels Bioprod
July 2024
State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
Background: 2-Phenylethanol (2-PE) is one of the most widely used spices. Recently, 2-PE has also been considered a potential aviation fuel booster. However, the lack of scientific understanding of the 2-PE biosynthetic pathway and the cellular response to 2-PE cytotoxicity are the most important obstacles to the efficient biosynthesis of 2-PE.
View Article and Find Full Text PDFInt J Equity Health
January 2024
Department of Health Management, School of Health Management, Southern Medical University, Guangzhou, 510515, China.
Objective: The aim of this study was to examine the Coronavirus disease 2019(COVID-19) vaccine policies disparities and effectiveness in Germany, Denmark and Bulgaria, with a view to providing lessons for global vaccination and response to possible outbreak risks.
Methods: This study analyzed big data through public information on the official websites of the Ministries of Health of the European Union, Germany, Denmark and Bulgaria and the official websites of the World Health Organization. We systematically summarized the COVID-19 vaccine policies of the three countries, and selected the following six indicators for cross-cutting vaccination comparisons: COVID-19 vaccine doses administered per 100 people, COVID-19 vaccination rate, the share of people with fully vaccinated, the share of people only partly vaccinated, cumulative confirmed COVID-19 cases per million, cumulative confirmed COVID-19 deaths per million.
Infect Dis Now
February 2024
Sorbonne Université, Centre d'Immunologie et des Maladies Infectieuses (Cimi-Paris), UMR 1135, Paris, France; AP-HP, Sorbonne-Université, Hôpital Saint-Antoine, Département de Bactériologie, Centre National de Référence des Mycobactéries et de la Résistance des Mycobactéries aux Antituberculeux, Hôpital Pitié-Salpêtrière, Paris, France.
Antibiotic-resistant tuberculosis continues to be one of the major threats to global tuberculosis control. After a hiatus of over 40 years in antituberculosis drug development, the last decade has seen a resurgence of research, yielding a number of promising compounds in the tuberculosis drug pipeline, with some that are now game changers in the treatment of MDRTB. Despite this progress, there are still obstacles restricting the use of these molecules as first-line drugs.
View Article and Find Full Text PDFBiomaterials
November 2023
Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China; The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, China; Department of Applied Biology and Chemical Technology, the Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China. Electronic address:
Stenting is the primary treatment for vascular obstruction-related cardiovascular diseases, but it inevitably causes endothelial injury which may lead to severe thrombosis and restenosis. Maintaining nitric oxide (NO, a vasoactive mediator) production and grafting endothelial glycocalyx such as heparin (Hep) onto the surface of cardiovascular stents could effectively reconstruct the damaged endothelium. However, insufficient endogenous NO donors may impede NO catalytic generation and fail to sustain cardiovascular homeostasis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!