Previous menthol studies have demonstrated ergogenic effects in endurance-based activity. However, there is a need for research in sports whose physiological requirements exceed maximal aerobic capacity. This study assessed the effects of 0.1% menthol mouth-rinsing upon a modified three-minute maximal test in the heat (33.0 ± 3.0 °C; RH 46.0 ± 5.0%). In a randomised crossover single blind placebo-controlled study, 11 participants completed three modified maximal tests, where each trial included a different mouth rinse: either menthol (MEN), cold water (WAT) or placebo (PLA). Participants were asked to rate their thermal comfort (TC), thermal sensation (TS) and rating of perceived exertion (RPE) throughout the test. Heart rate, core temperature, oxygen uptake (VO), ventilation (VE) and respiratory exchange ratio (RER) were monitored continuously throughout the test, alongside cycling power variables (W; W/kg). A blood lactate (BLa) level was taken pre- and post- test. Small to moderate effects (Cohen's and accompanying 90% confidence intervals) between solutions MEN, WAT and PLA were observed towards the end of the test in relation to relative power. Specifically, from 75-105 s between solutions MEN and WAT (ES: 0.795; 90% CI: 0.204 to 1.352) and MEN and PLA (ES: 1.059; 90% CI: 0.412 to 1.666), this continued between MEN and WAT (ES: 0.729; 90% CI: 0.152 to 1.276) and MEN and PLA (ES: 0.791; 90% CI: 0.202 to 1.348) from 105-135 s. Between 135-165 s there was a moderate difference between solutions MEN and WAT (ES: 1.058; 90% CI: 0.411 to 1.665). This indicates participants produced higher relative power for longer durations with the addition of the menthol mouth rinse, compared to cold water or placebo. The use of menthol (0.1%) as a mouth rinse showed small performance benefits for short duration high intensity exercise in the heat.
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http://dx.doi.org/10.3390/ijerph19063527 | DOI Listing |
Biochem Pharmacol
December 2024
Department of Physiology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Electronic address:
Obesity, characterized by excessive fat accumulation in white adipose tissue (WAT), is linked to numerous health issues, including insulin resistance (IR), and type 2 diabetes mellitus (DM2). The distribution of adipose tissue differs by sex, with men typically exhibiting android adiposity and pre-menopausal women displaying gynecoid adiposity. After menopause, women have an increased risk of developing android-type obesity, IR, and DM2.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2024
Department of Health, Kinesiology and Applied Physiology, Concordia University, Montreal, QC H4B 1R6, Canada.
Background: Preliminary research suggests that acupuncture can improve cardiovascular function. The purpose of our study was to determine if electroacupuncture can improve performance and post-exercise recovery.
Methods: Thirty-two healthy people participated in this study (14 men and 18 women, aged 23.
J Clin Endocrinol Metab
September 2024
Division of Endocrinology, Department of Medicine, Centre de recherche du Centre hospitalier universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Context: Little is known about the link between the endocannabinoid system and the in vivo metabolic function of white adipose tissue (WAT).
Objective: We aimed to evaluate whether endocannabinoids (EC) are linked to postprandial fatty acid metabolism and WAT metabolic function.
Design: Men and women, with (IGT, n=20) or without impaired glucose tolerance (NGT, n=20) underwent meal testing with oral and intravenous stable isotope palmitate tracers and positron emission tomography with intravenous [11C]-palmitate and oral [18F]-fluoro-thia-heptadecanoic acid to determine systemic and organ-specific dietary fatty acid (DFA) and non-esterified fatty acid (NEFA) metabolism and partitioning.
Eur J Radiol
August 2024
Radiology Department, Bioengineering Department, College of Medicine, University of Illinois at Chicago, Chicago, IL, United States; Bioengineering Department, College of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Purpose: To delineate the alterations in adipose and muscle tissue composition and functionality among healthy young men across varying exercise intensities, which help to elucidate the impact of exercise intensity on weight management and inform fitness planning.
Method: 3D Dixon MRI scans were performed on the neck and supraclavicular area in 10 high-intensity exercises (HIE) athletes, 20 moderate intensity exercises (MIE) athletes and 19 low-intensity exercises non-athlete male controls (NCM). Twelve imaging parameters, including the total volume of muscle, white adipose tissue (WAT), brown adipose tissue (BAT), and the mean fat-water fraction (FWF) within these tissues.
Biochem Pharmacol
May 2024
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. Electronic address:
Upper-body adiposity is adversely associated with metabolic health whereas the opposite is observed for the lower-body. The neck is a unique upper-body fat depot in adult humans, housing thermogenic brown adipose tissue (BAT), which is increasingly recognised to influence whole-body metabolic health. Loss of BAT, concurrent with replacement by white adipose tissue (WAT), may contribute to metabolic disease, and specific accumulation of neck fat is seen in certain conditions accompanied by adverse metabolic consequences.
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