We consider the "partial information decomposition" (PID) problem, which aims to decompose the information that a set of source random variables provide about a target random variable into separate redundant, synergistic, union, and unique components. In the first part of this paper, we propose a general framework for constructing a multivariate PID. Our framework is defined in terms of a formal analogy with intersection and union from set theory, along with an ordering relation which specifies when one information source is more informative than another. Our definitions are algebraically and axiomatically motivated, and can be generalized to domains beyond Shannon information theory (such as algorithmic information theory and quantum information theory). In the second part of this paper, we use our general framework to define a PID in terms of the well-known Blackwell order, which has a fundamental operational interpretation. We demonstrate our approach on numerous examples and show that it overcomes many drawbacks associated with previous proposals.
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http://dx.doi.org/10.3390/e24030403 | DOI Listing |
J Am Med Inform Assoc
December 2024
AI for Health Institute, Washington University in St Louis, St Louis, MO 63130, United States.
Objective: Early detection of surgical complications allows for timely therapy and proactive risk mitigation. Machine learning (ML) can be leveraged to identify and predict patient risks for postoperative complications. We developed and validated the effectiveness of predicting postoperative complications using a novel surgical Variational Autoencoder (surgVAE) that uncovers intrinsic patterns via cross-task and cross-cohort presentation learning.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
City University of Hong Kong, Department of Physics and Materials Science, 83 Tat Chee Ave, Kowloon Tong, 999077, Hong Kong, HONG KONG.
Redox-active covalent organic frameworks (COFs) have been demonstrated as promising organic electrodes in many electrochemical devices. However, their inherently low conductivity significantly hinders the full utilization of their internal redox-active sites. To address this issue, a simple solvothermal method is used to in situ polymerize 2,4,6-triformylphloroglucinol (TP) and p-phenylenediamine (PA) on the surface of carbon nanotubes (CNTs), generating a nanocable-like COF-based nanocomposite, TpPa-COF@CNT nanocables, which contain abundant β-ketoenamine groups.
View Article and Find Full Text PDFClin Pharmacol Ther
December 2024
Flatiron Health, New York, NY, USA.
Clinical research has historically failed to include representative levels of historically underrepresented populations and these inequities continue to persist. Ensuring representativeness in clinical trials is crucial for patients to receive clinically appropriate treatment and have equitable access to novel therapies; enhancing the generalizability of study results; and reducing the need for post-marketing commitments focused on underrepresented groups. As demonstrated by recent legislation and guidance documents, regulatory agencies have shown an increased interest in understanding how novel therapies will impact the patient population that will receive them.
View Article and Find Full Text PDFScand J Prim Health Care
December 2024
Department of Pharmacy, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Background: Multicomponent interventions are increasingly utilized to tackle the complexity of aging and co-morbid patients. However, descriptions of interventions are generally poor, making it difficult for healthcare providers to implement successful programs.
Objectives: This study aimed to explore the completeness of intervention description of pharmacist-facilitated medication reviews (MRs) in Nordic primary care settings.
BMC Geriatr
December 2024
Harbin Medical University, Daqing, Heilongjiang Province, China.
Background: Standardized and systematic quality assessments of chronic pain management, particularly among older adult populations, are lacking in resource-limited community settings. A specific set of indicators to evaluate the quality of chronic pain management in this population has yet to be developed. Therefore, the present study constructed a set of indicators to assess the quality of chronic pain management in Chinese community-dwelling older adults, providing a standardized reference and guidance for community health centers to manage chronic pain in this population.
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