The emergence of antimicrobial-resistant bacteria is an enormous challenge to public health. and are opportunistic pathogens in fish. They exert tremendous adverse effects on aquaculture production, owing to their acquired antibiotic resistance. A few Clinical and Laboratory Standards Institute (CLSI) epidemiological cut-off values (ECVs) against spp. are available. We evaluated antimicrobial susceptibility by establishing 8 ECVs using two analytical methods, normalized resistance interpretation and ECOFFinder. We detected antimicrobial resistance genes in two motile spp. isolated from aquatic animals. Results showed that 89.2% of and 75.8% of isolates were non-wild types according to the oxytetracycline ECV and ECV, respectively. The antimicrobial resistance genes included , , , , , , , , , , and . The most common gene in spp. isolates was , followed by . Some strains carried more than one gene, with - and - found in ; however, was not detected in any of the strains. Furthermore, 18.6% of and 24.2% of isolates showed presumptive multidrug-resistant phenotypes. The emergence of multidrug resistance among aquatic aeromonads suggests the spread of drug resistance and difficult to treat bacterial infections.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944483PMC
http://dx.doi.org/10.3390/antibiotics11030343DOI Listing

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