The emergence of antimicrobial-resistant bacteria is an enormous challenge to public health. and are opportunistic pathogens in fish. They exert tremendous adverse effects on aquaculture production, owing to their acquired antibiotic resistance. A few Clinical and Laboratory Standards Institute (CLSI) epidemiological cut-off values (ECVs) against spp. are available. We evaluated antimicrobial susceptibility by establishing 8 ECVs using two analytical methods, normalized resistance interpretation and ECOFFinder. We detected antimicrobial resistance genes in two motile spp. isolated from aquatic animals. Results showed that 89.2% of and 75.8% of isolates were non-wild types according to the oxytetracycline ECV and ECV, respectively. The antimicrobial resistance genes included , , , , , , , , , , and . The most common gene in spp. isolates was , followed by . Some strains carried more than one gene, with - and - found in ; however, was not detected in any of the strains. Furthermore, 18.6% of and 24.2% of isolates showed presumptive multidrug-resistant phenotypes. The emergence of multidrug resistance among aquatic aeromonads suggests the spread of drug resistance and difficult to treat bacterial infections.
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http://dx.doi.org/10.3390/antibiotics11030343 | DOI Listing |
Microb Cell Fact
January 2025
Human Microbiology Institute, New York, NY, 10014, USA.
Our previous studies revealed the existence of a Universal Receptive System that regulates interactions between cells and their environment. This system is composed of DNA- and RNA-based Teazeled receptors (TezRs) found on the surface of prokaryotic and eukaryotic cells, as well as integrases and recombinases. In the current study, we aimed to provide further insight into the regulatory role of TezR and its loss in Staphylococcus aureus gene transcription.
View Article and Find Full Text PDFBMC Plant Biol
January 2025
Agricultural College, Faculty of Agricultural College, Inner Mongolia Agricultural University, Hohhot, 010019, China.
Background: Drought stress is a major environmental constraint affecting crop yields. Plants in agricultural and natural environments have developed various mechanisms to cope with drought stress. Identifying genes associated with drought stress tolerance in potato and elucidating their regulatory mechanisms is crucial for the breeding of new potato germplasms.
View Article and Find Full Text PDFSci Rep
January 2025
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Large-scale surveillance and informed vector control approaches are urgently needed to ensure that national malaria programs remain effective in reducing transmission and, ultimately, achieving malaria elimination targets. In South America, Anopheles darlingi is the primary malaria vector and is responsible for the majority of Plasmodium species transmission. However, little is known about the molecular markers associated with insecticide resistance in this species.
View Article and Find Full Text PDFNat Microbiol
January 2025
Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Synechococcus is a significant primary producer in the oceans, coexisting with cyanophages, which are important agents of mortality. Bacterial resistance against phage infection is a topic of significant interest, yet little is known for ecologically relevant systems. Here we use exogenous gene expression and gene disruption to investigate mechanisms underlying intracellular resistance of marine Synechococcus WH5701 to the Syn9 cyanophage.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Department of Medical Microbiology, Second Faculty of Medicine, Charles University and Motol University Hospital, Czech Republic. Electronic address:
Public transport represents a potential site for the transmission of resistant pathogens due to the rapid movement of large numbers of people. This study aimed to investigate the bacterial contamination of frequently touched surfaces in the public transport system operating in the proximity of the biggest Czech hospital during the coronavirus pandemic despite extensive cleaning and disinfection efforts. In June and September 2020, samples from the metro trains, ground transport and stationary objects were collected, enriched and cultured.
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