AI Article Synopsis
- The study aimed to analyze the presence and persistence of carbapenemase-producing bacteria in wastewater from two hospitals in Mexico, focusing on various bacterial isolates from treated and untreated wastewater.
- Out of 30 bacterial isolates examined, a high resistance rate (80%) to cephalosporins and carbapenems was found, with resistance genes identified using PCR and a variety of molecular typing methods.
- The research highlights the importance of monitoring hospital wastewater for antimicrobial resistance, which can serve as an early detection system for potential outbreaks and difficult infections.
Article Abstract
The objective of this study was to investigate the presence and persistence of carbapenemase-producing spp. isolated from wastewater and treated wastewater from two tertiary hospitals in Mexico. We conducted a descriptive cross-sectional study in two hospital wastewater treatment plants, which were sampled in February 2020. We obtained 30 spp. isolates. Bacterial identification was carried out by the Matrix-Assisted Laser Desorption/Ionization-Time of Flight mass spectrometry (MALDI-TOF MS) and antimicrobial susceptibility profiles were performed using the VITEK2 automated system. The presence of carbapenem resistance genes (CRGs) in spp. isolates was confirmed by PCR. Molecular typing was determined by pulsed-field gel electrophoresis (PFGE). High rates of spp. resistance to cephalosporins and carbapenems (80%) were observed in isolates from treated wastewater from both hospitals. The molecular screening by PCR showed the presence of and genes. The PFGE pattern separated the isolates into 19 patterns (A-R) with three subtypes (C1, D1, and I1). Microbiological surveillance and identification of resistance genes of clinically important pathogens in hospital wastewater can be a general screening method for early determination of under-detected antimicrobial resistance profiles in hospitals and early warning of outbreaks and difficult-to-treat infections.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944648 | PMC |
| http://dx.doi.org/10.3390/antibiotics11030288 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative analysis of hospital laboratory wastewater treatment techniques in Syrian Arab Republic.
East Mediterr Health J
December 2024
Department of Basic Sciences, Faculty of Civil Engineering, University of Aleppo, Aleppo, Syria.
Background: Hospital wastewater poses a significant threat to human health due to the presence of difficult-to-degrade organic compounds, active pharmaceutical ingredients and multiple inorganic substances that can pollute water resources and ecosystems.
Aim: To compare the effectiveness of different techniques for removing organic load from hospital laboratory wastewater in Aleppo, Syria.
Methods: We treated wastewater samples from hospital laboratories at Aleppo University Hospital, Syria, using several techniques, including biological treatment with the rotating biological contactor, adsorption with Syrian natural clay, coagulation with aluminium sulphate, advanced oxidation with ultrasound, and a combined treatment using natural clay and ultrasound.
Expanded Negative Electrostatic Network-Assisted Seawater Oxidation and High-Salinity Seawater Reutilization.
ACS Nano
January 2025
College of Chemistry Chemical Engineering and Materials Science, Shandong Normal University, Jinan, Shandong 250014, China.
Coastal/offshore renewable energy sources combined with seawater splitting offer an attractive means for large-scale H electrosynthesis in the future. However, designing anodes proves rather challenging, as surface chlorine chemistry must be blocked, particularly at high current densities (). Additionally, waste seawater with increased salinity produced after long-term electrolysis would impair the whole process sustainability.
View Article and Find Full Text PDFHydroxytyrosol-rich Olive Mill Wastewater, A Potential Protector Against Dyslipidemia, Diabetes and Diabetic Retinopathy in Psammomys obesus.
Chem Biodivers
January 2025
University of Manouba Higher Institute of Biotechnology of Sidi Thabet, Laboratory of Physiopathology, Food and Biomolecules, BiotechPolet, BP-66, 2020, Sidi Thabet,, 2020, Ariana, TUNISIA.
Olive mill wastewater (OMWW), a byproduct of olive oil extraction, constitutes a natural resource of phenolic compounds. Hydroxytyrosol (HT), the predominant compound, exhibits antioxidant, anti-inflammatory, and neuroprotective effects. This research aims to evaluate the effect of OMWW bioproduct rich in HT on retinal glial function, glutamate metabolism and synaptic transmission alterations mediated by hyperglycemia and dyslipidemia in high-calorie diet (HCD) induced diabetic retinopathy (DR) in Psammomys obesus.
View Article and Find Full Text PDFIsolation and characterization of Acinetobacter phage vAbaIN10 active against carbapenem Resistant Acinetobacter baumannii (CRAB) isolates from healthcare-associated infections in Dakar, Senegal.
J Glob Antimicrob Resist
December 2024
Pôle de Microbiologie, Institut Pasteur de Dakar, Sénégal; Faculté de Médecine, Pharmacie et Odontostomatologie, Université Cheikh Anta Diop, Dakar, Sénégal.
Article Synopsis
- Acinetobacter baumannii, especially the carbapenem-resistant strains (CRAB), is a critical pathogen linked to antimicrobial resistance (AMR) and is prioritized by the WHO.
- Phage therapy is being explored as a potential treatment for CRAB infections due to increasing resistance to conventional antibiotics.
- A newly isolated lytic phage, vAbaIN10, exhibits effective lytic activity against CRAB in various conditions and shows promise in advancing treatment options for multidrug-resistant infections.
Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health.
Imeta
December 2024
Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen China.
The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!