AI Article Synopsis

  • Two ICU patients with COVID-19 developed serious eye conditions: endogenous endophthalmitis in one eye and chorioretinitis in the other.
  • Both patients, aged 57 and 62, had underlying diabetes and exhibited symptoms like anterior uveitis and subretinal infiltrations.
  • High serum galactomannan levels indicated aspergillosis, raising concerns that high corticosteroid use for COVID-19 treatment may increase the risk of secondary fungal infections impacting the eyes.

Article Abstract

We present two ICU-hospitalized patients with coronavirus disease-19 (COVID-19) presenting with endogenous endophthalmitis in one eye and variable manifestations of chorioretinitis in the fellow eye. Two diabetic patients (57 and 62 years old) showed anterior uveitis and yellowish-white subretinal infiltrations. The fellow eye of one patient showed patches of choroiditis, while the other showed full retinal thickness infiltrations. A workup yielded high serum titers of galactomannan, diagnostic of aspergillosis. The widespread use of high doses of corticosteroids in the management of COVID-19 may predispose to various secondary fungal opportunistic infections and may manifest in different forms of chorioretinal infiltration.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240524PMC
http://dx.doi.org/10.4103/ijo.IJO_2718_21DOI Listing

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