AI Article Synopsis

  • The study reviews literature to determine how often pT0 stage occurs in patients post-radical prostatectomy and its outcomes.
  • The incidence of pT0 is low, found in 0.07% to 1.3% of cases, with predictors including low-grade cancer in a single biopsy core and high prostate volume.
  • While the prognosis for pT0 patients is generally excellent, regular follow-up is recommended due to the unpredictable nature of this finding.

Article Abstract

(1) Background: Following radical prostatectomy (RP), the absence of a demonstrable tumor on the specimen of a previously histologically proven malignancy is known as the pT0 stage. The aim of our present study is to perform a narrative review of current literature in order to determine the frequency and oncological outcomes in patients with pT0 disease. (2) Methods: A narrative review of all available literature was performed. (3) Results: The incidence of pT0 ranges between 0.07% and 1.3%. Predictors of the pT0 stage are only a single biopsy core with low-grade cancer, a cancer length not exceeding 2 mm and a high prostate volume. Biochemical recurrence ranges between 0 and 11%. (4) Conclusions: The absence of malignancy in the RP specimen despite a previous positive biopsy is a rare and unpredictable finding. Although the prognosis is considered to be excellent in most of the cases, a continued close follow-up is warranted.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946857PMC
http://dx.doi.org/10.3390/curroncol29030111DOI Listing

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