UV-VIS Curable PEG Hydrogels for Biomedical Applications with Multifunctionality.

Gels

Nanopatterned Biomaterials (Secr. C 1), Department of Chemistry, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin, Germany.

Published: March 2022

Multifunctional biomedical materials capable of integrating optical functions are highly desirable for many applications, such as advanced intra-ocular lens (IOL) implants. Therefore, poly(ethylene glycol)-diacrylate (PEG-DA) hydrogels are used with different photoinitiators (PI). In addition to standard UV PI Irgacure, Erythrosin B and Eosin Y are used as PI with high sensitivity in the optical range of the spectrum. The minimum PI concentrations for producing new hydrogels with PEG-DA and different PIs were determined. Hydrogel films were obtained, which were applicable for light-based patterning and, hence, the functionalization of surface and volume. Cytotoxicity tests confirm cytocompatibility of hydrogels and compositions. Exploiting the correlation of structure and function allows biomedical materials with multifunctionality.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956119PMC
http://dx.doi.org/10.3390/gels8030164DOI Listing

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