Aim: The present narrative review aims to provide an overview of the in vivo accuracy of full-arch scans performed with currently used intraoral devices and to compare different methods for the determination of in vivo accuracy. Materials and methods: An electronic search was performed with the PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science databases, including articles from 2015 to 2020. Specific search strategies were developed for each platform.
Results: The final search resulted in five published articles. The mean values of trueness and precision of the examined scanners ranged from 12.9 to 80.01 µm for trueness and from 42.9 to 86.0 µm for precision in full-arch dentition. Not all studies evaluated both trueness and precision. Furthermore, the methods and references for determining the in vivo accuracy proved to be very different.
Conclusion: To date, no scientific consensus on the required accuracy of in vivo full-arch scans has been reached and published. Due to the small number of studies on the in vivo accuracy of full-arch scans, further studies should be conducted in this area. In addition, a concept for a valid reference that can be scanned both extraorally and intraorally should be developed.
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J Inflamm Res
January 2025
Department of Pain Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530007, People's Republic of China.
Purpose: Intestinal ischemia-reperfusion injury (IIRI) occurs as a result of temporary blood flow interruption, leading to tissue damage upon reperfusion. Oxidative stress plays a critical role in this process, instigating inflammation and cell death. Identifying and characterizing genes associated with the oxidative stress response can offer valuable insights into potential therapeutic targets for managing IIRI.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Department of Pharmacy, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Background: Ripretinib, a broad-spectrum tyrosine kinase inhibitor, has been approved for the treatment of advanced gastrointestinal stromal tumors in adult patients. Clinical studies have shown that higher exposure of ripretinib correlates with improved efficacy, highlighting the potential clinical significance of therapeutic drug monitoring. In this study, a simple and stable liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was attempted to be established and validated for pharmacokinetic studies of ripretinib and its metabolite DP-5439 and therapeutic drug monitoring in human plasma.
View Article and Find Full Text PDFMethodsX
June 2025
Regenerative Bioscience Center, Department of Animal and Dairy Science, College of Agricultural and Environmental Science, University of Georgia, Athens, GA 30602, United States.
Muscle strength is a crucial metric for assessing motor function, with significant diagnostic and prognostic value. It is widely used in clinical and preclinical studies as a phenotypic indicator. In mouse models of neuromuscular disorders, grip strength provides a direct, repeatable measure of motor function changes throughout disease progression.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Department of Neurosurgery, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, China.
Brain biopsy is commonly employed for the histological diagnosis of complex intracranial diseases. To improve the positive diagnostic rate, the precision of intraoperative tissue sampling is critical. This study evaluated the accuracy of fluorescence imaging technology in rapidly distinguishing tumours from nontumour tissue during surgery, thus providing real-time feedback to surgeons and optimizing the surgical workflow.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
January 2025
CAS Key Laboratory of Molecular Imaging, Beijing Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, No.95 Zhongguancun East Road, Hai Dian District, Beijing, 100190, China.
Purpose: Precise tumor excision is important but challenging in breast-conserving surgery (BCS). Tumor-specific fluorescence imaging may be used for intraoperative tumor detection and, therefore, to guide precise tumor excision. The aims of this study are to develop a glucose transporter 1 (GLUT1)-targeted near-infrared fluorescence tracer and evaluate its accuracy for breast cancer detection using fresh surgical breast specimens.
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