AI Article Synopsis
- The study examined the characteristics and care of patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) in two hospitals in Nepal, focusing on adherence to international treatment guidelines.
- Out of 108 patients, most were older males with a history of smoking, and the majority were classified as having severe COPD; nearly all received necessary treatments such as oxygen, beta2 agonists, antibiotics, and corticosteroids.
- While guidelines were largely followed, uncertainties about treatment indications raise questions about potential over-treatment or the severity of the patients’ conditions.
Article Abstract
Objectives: Chronic obstructive pulmonary disease is a large and increasing problem in low- and middle-income countries; Nepal is no exception. We aimed to obtain information on patient characteristics and the level of care provided to patients admitted for acute exacerbation of chronic obstructive pulmonary disease in two Nepalese hospitals and to compare the given care with the Global Initiative for Chronic Obstructive Lung Disease guidelines.
Methods: This was a cross-sectional, observational, descriptive study. All patients admitted to two Nepalese hospitals due to acute exacerbation of chronic obstructive pulmonary disease between 18 February and 5 April 2019 were asked to participate.
Results: In total, 108 patients with a median age of 70 years participated. Fifty-three (42.7%) were male, 80 (74.8%) were former smokers, and 46 (45.1%) were farmers. Using the Global Initiative for Chronic Obstructive Lung Disease A-D classification, 97 (90.6%) of the patients were classified in group D. All the patients received supplementary oxygen treatment and 103 (95.4%) were treated with short-acting beta2 agonists. A total of 105 (97.2%) patients received antibiotics, and 80 (74.5%) received systemic corticosteroids. The majority was discharged with triple therapy including long-acting muscarinic antagonist, long-acting beta2 agonist, and inhaled corticosteroids, and 72 (75.8%) were discharged with long-term oxygen treatment.
Conclusion: All elements of the Global Initiative for Chronic Obstructive Lung Disease guidelines were applied. However, due to a lack of information, it cannot be concluded whether the treatment was provided on the correct indications. The average patient received almost all the treatment alternatives available. This might indicate a very sick population or over-treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935543 | PMC |
| http://dx.doi.org/10.1177/20503121221085087 | DOI Listing |
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