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Development of a new data management system for the study of the gut microbiome of children who are small for their gestational age.
Comput Struct Biotechnol J
December 2024
Institute of Bioinformatics, University of Münster, Münster, Germany.
Microbiome studies aim to answer the following questions: which organisms are in the sample and what is their impact on the patient or the environment? To answer these questions, investigators have to perform comparative analyses on their classified sequences based on the collected metadata, such as treatment, condition of the patient, or the environment. The integrity of sequences, classifications, and metadata is paramount for the success of such studies. Still, the area of data management for the preliminary study results appears to be neglected.
View Article and Find Full Text PDFElectrochemical aptasensor for the selective detection of vancomycin based on nanostructured "in-lab" printed electrodes.
Mikrochim Acta
January 2025
Department of Analytical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 4 Pasteur Street, 400349, Cluj-Napoca, Romania.
A label-free, flexible, and disposable aptasensor was designed for the rapid on-site detection of vancomycin (VAN) levels. The electrochemical sensor was based on lab-printed carbon electrodes (C-PE) enriched with cauliflower-shaped gold nanostructures (AuNSs), on which VAN-specific aptamers were immobilized as biorecognition elements and short-chain thiols as blocking agents. The AuNSs, characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM), enhanced the electrochemical properties of the platform and the aptamer immobilization active sites.
View Article and Find Full Text PDFDevelopment of a novel HPLC-HRMS method for quantitative analysis of resorcinol in urine: Application to hairdressers' occupational exposure.
J Chromatogr B Analyt Technol Biomed Life Sci
January 2025
Resorcinol is a widespread substance used in a large variety of manufacturing industries, including cosmetics, with endocrine-disrupting activity on the thyroid function. The aim of the present study was to develop and validate a sensitive, selective and robust method to quantify resorcinol in urine and thereby assess hairdressers' occupational exposure. As resorcinol is mainly excreted in urine as glucuronide or sulfate forms, the first step consisted in hydrolyzing urine samples with a β-glucuronidase-arylsulfatase enzyme for 16 h.
View Article and Find Full Text PDFA Review of Miniature Radio Transmitters for Wildlife Tracking.
Sensors (Basel)
January 2025
The Blavatnik School of Computer Science and AI, Tel Aviv University, Tel Aviv 69978, Israel.
This article surveys the literature on miniature radio transmitters designed to track free-ranging wild animals using emitter-localization techniques. The articles covers the topics of power sources used in such transmitters, including miniature batteries and energy harvesting, techniques for generating the transmitted radio-frequency carrier, techniques for creating short radio pulses and more general on-off schedules, modulation in modern wildlife-tracking transmitters, construction, manufacturing, and tuning techniques, and recent trends in this area. The article also describes the recreation of the first successful wildlife-tracking transmitter, a nontrivial invention that had a profound impact on wildlife ecology, and explores its behavior.
View Article and Find Full Text PDFA Method to Evaluate Orientation-Dependent Errors in the Center of Contrast Targets Used with Terrestrial Laser Scanners.
Sensors (Basel)
January 2025
Sensor Science Division, National Institute of Standards and Technology, Gaithersburg, MD 20878, USA.
Terrestrial laser scanners (TLS) are portable dimensional measurement instruments used to obtain 3D point clouds of objects in a scene. While TLSs do not require the use of cooperative targets, they are sometimes placed in a scene to fuse or compare data from different instruments or data from the same instrument but from different positions. A contrast target is an example of such a target; it consists of alternating black/white squares that can be printed using a laser printer.
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