This essay brings together different voices to reflect on several participatory research projects carried out in Colombia, based on human rights, 'empowerment', harm reduction, (im)mobility and forced migration, gendered and political violence, armed conflict, and the right to health of people in the social margins. We look back on nine years of activism to explore the foundations of what our friendships and relationships have come to know as a revolutionary ethos. We critically re-visit and reflect on the concept of 'the activist' in the realms of the human rights apparatus in Colombia, the academy and the Non-Profit Industrial Complex (NPIC). We look back on what was forged and what was lost to propose the critical concept of 'radical honesty and self-care' as the basis for a revolution that supports processes of healing and social justice. Finally, we imagine what 'healing' can look like, as committed activists despite our differences and positionalities. We engage with and problematise the different forms of activism that emerge in social struggles and we address self-criticisms, constant reflection, radical honesty and uncomfortableness as powerful tools in joining forces to continue social justice work and caring.
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http://dx.doi.org/10.1080/17441692.2022.2042354 | DOI Listing |
Zhonghua Yi Xue Za Zhi
January 2025
Public Health Emergency Management Innovation Center, Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, State Key Laboratory of Respiratory Health and Multimorbidity, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100730, China.
The elderly population in China faces a significant burden of influenza, but the influenza vaccination rate among this group remains far below international recommended standards due to factors such as the underdeveloped adult immunization service system, high vaccination costs, and insufficient awareness among both the elderly and healthcare professionals. It is recommended that China implement a free or reimbursement policy influenza vaccination for elderly in border regions, improve the adult immunization service system, enhance the awareness of healthcare professionals and the elderly, and strengthen the research and post-vaccination monitoring of vaccines tailored to the elderly population to increase the influenza vaccination rate among the elderly.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
January 2025
Public Health Emergency Management Innovation Center, Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, State Key Laboratory of Respiratory Health and Multimorbidity, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100730, China.
The prevalence and evolution of respiratory pathogens are changing, and issues related to drug-resistance are becoming increasingly prominent in the post-COVID era. The urgency of controlling respiratory pathogens has intensified. This issue organizes expert discussions to address the resurgence of various respiratory pathogens, summarizing current status of pathogen surveillance, drug-resistance research and vaccine development, while suggesting countermeasures.
View Article and Find Full Text PDFNat Rev Genet
January 2025
Altos Labs, Cambridge, UK.
Over the past decade, epigenetic clocks have emerged as powerful machine learning tools, not only to estimate chronological and biological age but also to assess the efficacy of anti-ageing, cellular rejuvenation and disease-preventive interventions. However, many computational and statistical challenges remain that limit our understanding, interpretation and application of epigenetic clocks. Here, we review these computational challenges, focusing on interpretation, cell-type heterogeneity and emerging single-cell methods, aiming to provide guidelines for the rigorous construction of interpretable epigenetic clocks at cell-type and single-cell resolution.
View Article and Find Full Text PDFBMC Nephrol
January 2025
Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Key Laboratory of Organ Transplantation, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Huazhong University of Science and Technology, Ministry of Education, Chinese Academy of Medical Sciences, Wuhan, China.
Background: Effective treatment of late antibody-mediated rejection (late AMR) is still an unmet medical need. Clearing donor-specific antibody (DSA) and preventing its rebound is the ideal goal of treatment.
Methods: We have summarized the clinical data from seven patients with late or chronic active AMR after renal transplantation who received daratumumab (Dara)-based treatment first (Phase 1) and then tocilizumab (TCZ) therapy (Phase 2).
Int J Mol Sci
January 2025
Institute of Immunology, Faculty of Medicine, Comenius University Bratislava, 813 72 Bratislava, Slovakia.
Gliomas are the most common and lethal forms of malignant brain tumors. We attempted to identify the role of the aging-suppressor gene and Klotho protein in the immunopathogenesis of gliomas. We examined genetic variants by PCR-RFLP and measured serum Klotho levels using the ELISA method.
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