Three new compounds isolated from the whole plants of pall.

One new alkaloid, 6, 7-dimethoxyisoquinoline--oxide (), one new benzofuran derivative, 3,7-dimethyl-6-acetyl-8-benzofuranol () and one new lignan, salsolains A (), along with seven known compounds (-), were isolated from the whole plant of Pall. Their structures were elucidated by extensive analysis of spectroscopic data (IR, UV, HR-ESI-MS, 1 D and 2 D NMR), and their absolute configurations were determined by the X-ray crystallography and ECD calculation. The activities of compounds - against inflammatory cytokines IL-6 and TNF- levels on LPS-induced RAW 264.7 macrophages were assessed, especially, compound (50 μM) exhibited the most significant anti-inflammatory activity with the secretion levels of IL-6 and TNF- at 3.87% and 4.03%, respectively.