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Diffusion-weighted Imaging Voxelwise-matched Analyses of Lung Cancer at 3.0-T PET/MRI: Reverse Phase Encoding Approach for Echo-planar Imaging Distortion Correction.

Radiology

June 2020

From the Dept of Biophysics and Nuclear Medicine-Molecular Imaging, Hôpitaux Universitaires Paris-Saclay, Assistance Publique-Hôpitaux de Paris, CHU Bicêtre, 94270, Le Kremlin-Bicêtre, France (F.L.B., E.D.); Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France (F.L.B., O.M., A.S., S.B., S.M., F.P., D. Montani, D. Mitiliian, E.F., V.L., E.D.), Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Orsay, 91401, France (F.L.B., C.C., V.L., E.D.); Applications and Workflow, GE Healthcare, Buc, France (B.F.); Laboratoire de Mathématiques d'Orsay, Université Paris-Saclay CNRS, 91405 Orsay, France (S.F.); Dept of Thoracic and Vascular Surgery and Heart-Lung Transplantation, Hôpital Marie Lannelongue, 92350 Le Plessis Robinson, France (O.M., S.M., D. Mitilian, E.F.); Dept of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpitaux Universitaires Paris-Saclay, Assistance Publique-Hôpitaux de Paris, CHU Bicêtre, 94270, Le Kremlin-Bicêtre, France (A.S., X.M., S.B., F.P., D. Montani); Inserm UMR_S999 Pulmonary Hypertension: Pathophysiology and Novel Therapies, Hôpital Marie Lannelongue, 92350 Le Plessis Robinson, France (A.S., D. Montani); Service Hospitalier Frédéric Joliot (SHFJ), CEA/Université Paris-Saclay, Orsay, France (É.B., A.C., F.B., V.L.); Dept of Pathology, Hôpital Marie Lannelongue, 92350 Le Plessis Robinson, France (M.R.G.B.); NeuroSpin, CEA Saclay, Université Paris-Saclay, Gif-sur-Yvette, France and Parietal, INRIA, Palaiseau, 91120, France (H.C.).

Background PET/MRI has drawn increasing interest in thoracic oncology due to the simultaneous acquisition of PET and MRI data. Geometric distortions related to diffusion-weighted imaging (DWI) limit the evaluation of voxelwise multimodal analyses. Purpose To assess the effectiveness of reverse phase encoding in correcting DWI geometric distortion for multimodal PET/MRI voxelwise lung tumor analyses.

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