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http://dx.doi.org/10.1186/s12877-022-02856-4 | DOI Listing |
Int J Clin Health Psychol
December 2024
Medical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Previous research has found that compulsions in obsessive-compulsive disorder (OCD) are associated with an imbalance between goal-directed and habitual responses. However, the cognitive mechanisms underlying how goal-directed and habitual behaviors are learned, and how these learning deficits affect the response process, remain unclear. The present study aimed to investigate these cognitive mechanisms and examine how they were involved in the mechanism of compulsions.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Effectively responding to drug-resistant tuberculosis (TB) requires accurate and timely information on resistance levels and trends. In contexts where use of drug susceptibility testing has not been universal (i.e.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
J Infect Dis
December 2024
Department of Infection Biology, London School of Hygiene and Tropical Medicine, United Kingdom.
Background: Malaria remains a major public health concern with substantial morbidity and mortality worldwide. In Malaysia, the emergence of Plasmodium knowlesi has led to a surge in zoonotic malaria cases and deaths in recent years. Signs of cerebral involvement have been observed in a noncomatose, fatal case of knowlesi infection, but the potential impact of this malaria species on the brain remains unexplored.
View Article and Find Full Text PDFBrain Behav Immun Health
December 2024
Ace Alzheimer Center Barcelona-Universitat Internacional de Catalunya, Barcelona, Spain.
Despite the central role attributed to neuroinflammation in the etiology and pathobiology of Alzheimer's disease (AD), the direct link between levels of inflammatory mediators in blood and cerebrospinal fluid (CSF) compartments, as well as their potential implications for AD diagnosis and progression, remains inconclusive. Moreover, there is debate on whether inflammation has a protective or detrimental effect on disease onset and progression. Indeed, distinct immunological mechanisms may govern protective and damaging effects at early and late stages, respectively.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!