The purpose of this study was to quantify the relationship between a drop in end-tidal carbon dioxide (etCO) and occlusion of pulmonary veins (PVs) to find a delta etCO (ΔetCO) able to predict occlusion during PV isolation (PVI) by cryoballoon. We designed a prospective registry. Paroxysmal atrial fibrillation patients who underwent cryoballoon PVI were included. Capnography was performed. Occlusion was tested by injection. A comparison between ΔetCO and occlusion was performed. Eighteen subjects (138 injections) were included. A drop of >3.5 mmHg predicted occlusion of the PV (sensitivity, 80%; specificity, 86.7%). A ΔetCO of ≥3.5 mmHg during inflation of the cryoballoon in each PV directly correlates with PV balloon occlusion.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930007PMC
http://dx.doi.org/10.19102/icrm.2022.130402DOI Listing

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