AI Article Synopsis
- A 13-year-old girl diagnosed with IRVAN struggled with central vision loss for 10 months and had poor responses to previous steroid treatments.
- She was initially treated with intravitreal dexamethasone and oral Mycophenolate Mofetil but showed only temporary improvement.
- The patient's condition was successfully managed with a new combination therapy of Adalimumab and Azathioprine, marking the first documented case of this approach for IRVAN treatment.
Article Abstract
Purpose: To report a case of IRVAN in a 13-year-old girl responding well to Adalimumab and Azathioprine.
Results: A 13-year-old girl presented to us with central scotoma for a duration of 10 months. She was treated earlier with oral steroids with poor response. Fundus examination revealed features of IRVAN. She was treated with intravitreal dexamethasone implant in both eyes with oral Mycophenolate Mofetil (MMF) with transient response to it. So she was switched over to subcutaneous Adalimumab 40 mg once in 2 weeks and oral Azathioprine 50 mg BD. The disease activity was well controlled with the current regime.
Conclusion: Though various treatment modalities have been described in literature for the treatment of IRVAN. This is the first case of IRVAN to be treated with Adalimumab along with Azathioprine to be reported.
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| http://dx.doi.org/10.1080/09273948.2022.2039209 | DOI Listing |
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