An 85-year-old woman presented with pain and a palpable mass in her left flank. Abdominal computed tomography revealed massive splenomegaly and para-aortic lymphadenopathies. Bone marrow biopsy showed CD79a, CD20, and bcl-2-positive atypical lymphocytes, which led to the diagnosis of splenic marginal zone lymphoma.
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http://dx.doi.org/10.1002/ccr3.5512 | DOI Listing |
Am J Case Rep
December 2024
I Department of Radiology and Diagnostic Imaging, Norbert Barlicki Memorial Teaching Hospital No. 1, Medical University of Łódź, Łódź, Poland.
BACKGROUND Arterioportal fistulas (APFs) are abnormal connections between the arterial and portal venous systems, leading to portal hypertension (PH) and symptoms such as gastrointestinal bleeding, splenomegaly, and hepatic pain. Symptoms typically appear by the age of 2 years in about 75% of cases. CASE REPORT A 7-year-old boy with an asymptomatic APF developed life-threatening complications following a Clostridium difficile infection.
View Article and Find Full Text PDFHepatol Res
November 2024
Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan.
Partial splenic embolization (PSE) has developed as an alternative to surgical splenectomy, mainly to improve hypersplenism and esophagogastric varices in cirrhotic patients. We proposed the novel concept that splenic infarction volume, rather than the splenic infarction ratio, is essential for patients receiving PSE. A splenic infarction volume between 388 and 540 mL is suitable for a sufficient increase in platelet count and less severe PSE-related complications.
View Article and Find Full Text PDFRadiol Case Rep
January 2025
Faculty of Diagnostic Radiology, University of Calgary, Calgary, Alberta, Canada.
A 51-year-old man, with a history of cirrhotic portal hypertension and recurrent transjugular intrahepatic portosystemic shunt (TIPS) stenoses, presented with an acute gastro-esophageal variceal hemorrhage in the setting of an acute and massive thrombotic TIPS shunt occlusion. The clinical presentation was complicated by patient's severe, chronic thrombocytopenia which had precluded empiric anticoagulation previously for recurrent TIPS dysfunction. Following endoscopic treatment of the variceal bleeding, the CAT 12 Indigo aspiration system (Penumbra) was used to remove a large burden of thrombus from the TIPS, allowing successful re-stenting and restoration of blood flow through the TIPS.
View Article and Find Full Text PDFNatl Med J India
October 2024
General Medicine, Institute of Medical Sciences and SUM Hospital, Kalinga Nagar, Bhubaneswar 751003, Odisha, India.
Scrub typhus is still an underdiagnosed disease despite an increase in incidence as the clinical presentation is often different, leading to a low index of suspicion among doctors. Scrub typhus, an acute febrile disease, is a cause of prolonged fever and pyrexia of unknown origin. It can have varied clinical presentations ranging from mild asymptomatic disease to fatal multi-organ dysfunction.
View Article and Find Full Text PDFGenes (Basel)
September 2024
Center of Pediatric Hematology Oncology, Azienda Policlinico di Catania, 95100 Catania, Italy.
Noonan syndrome (NS) is an autosomal dominant disorder that varies in severity and can involve multiple organ systems. In approximately 50% of cases, it is caused by missense mutations in the gene (12q24.13).
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