Scleral remodeling in myopia development.

Int J Ophthalmol

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

Published: March 2022

AI Article Synopsis

  • Myopia is becoming a major global health issue due to its rising prevalence, primarily linked to increased axial length of the eye.
  • Changes in the scleral extracellular matrix (ECM) are crucial for scleral remodeling, which is associated with the development and worsening of nearsightedness.
  • This review highlights recent research on scleral remodeling to identify potential prevention and treatment strategies for myopia.

Article Abstract

With the increasing prevalence in recent years, myopia has become an essential global health concern. In most instances, an increased axial length of the eye is the structural cause of nearsightedness. The scleral remodeling, primarily dependent on the scleral extracellular matrix (ECM) changes, is significantly linked to eye lengthening. Scleral remodeling plays a critical function in the incidence and progression of myopia. This mini-review will focus on recent research progress of scleral remodeling in the hope of providing new ideas for the prophylaxis and treatment of myopia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907044PMC
http://dx.doi.org/10.18240/ijo.2022.03.21DOI Listing

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