AI Article Synopsis

  • Deliberate self-poisoning and harm (DSPH) is a serious and ongoing issue, particularly among young to middle-aged individuals, with a study analyzing cases from 2017 to 2018 to identify the methods used in a specific area.
  • The research found that agrochemicals and drugs were the most common substances used for self-harm, with significant medical interventions often required in emergency situations, including intubation and vasopressor support.
  • Results indicated a 3% mortality rate in the hospital, with rodenticides and plant toxins identified as the main predictors of death, highlighting the severity of these methods in DSPH cases.

Article Abstract

Background: Deliberate self-poisoning and harm (DSPH) is an unabating problem with a wide variation in the methods used across the world. Hence, this study was conducted to understand the current spectrum of methods used for DSPH by patients in our geographic locality and catchment area with special emphasis on newer compounds and drugs used.

Methods: This retrospective study included patients presenting with DSPH to the emergency department (ED) between January 2017 and December 2018.

Results: This study included 1802 patients, with a mean age of 32 ± 12.7 years. Of the patients, 85% were in the young to middle age group (16-45 years). Agrochemicals (n = 604, 33.5%), drugs (n = 498, 27.6%), plant toxins (n = 150, 8.3%) and rodenticides (n = 145, 8%) were the predominantly used compounds. The major emergency resuscitation procedures required in the ED were intubation (n = 321, 18%), vasopressor support (n = 73, 4%) and cardiopulmonary resuscitation (n = 27, 1.4%). A quarter (23.2%) was discharged stable from the ED, whereas a further 56.5% were discharged stable after hospital admission. The in-hospital mortality rate was 3% (n = 47). Multivariate logistic regression analysis showed rodenticides (odds ratio (OR): 22.32; 95% confidence interval (CI): 8.05-61.88; = 0.005) and plant poisons (OR: 23.92; 95% CI: 8.95-63.94; = 0.005) to be the independent predictors of mortality.

Conclusion: DSPH is prevalent in the highly productive young age group. Agrochemical ingestion and drug overdose are the most common methods used, whereas rodenticide and plant poisoning are associated with significant mortality.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930158PMC
http://dx.doi.org/10.4103/jfmpc.jfmpc_1184_21DOI Listing

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