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http://dx.doi.org/10.3389/fpubh.2022.852840 | DOI Listing |
Pharmaceut Med
January 2025
Pharmaceutical Medicine, Dover Heights, Sydney, NSW, Australia.
Pharmaceutical medicine professionals have to face many ethical problems during the entire life span of new medicines extending from animal studies to broad clinical practice. The primary aim of the general ethical principles governing research conducted in humans is to diminish the physical and psychological burdens of the participants in human drug studies but overlooks many additional social and ethical problems faced by medicine developers. These arise mainly at the interface connecting the profit-oriented pharmaceutical industry and the healthcare-centered medical profession cooperating in medicines development.
View Article and Find Full Text PDFFront Cardiovasc Med
January 2025
Department of Artificial Intelligence and Informatics, Mayo Clinic, Jacksonville, FL, United States.
Background: Effective management of dual antiplatelet therapy (DAPT) following drug-eluting stent (DES) implantation is crucial for preventing adverse events. Traditional prognostic tools, such as rule-based methods or Cox regression, despite their widespread use and ease, tend to yield moderate predictive accuracy within predetermined timeframes. This study introduces a new contrastive learning-based approach to enhance prediction efficacy over multiple time intervals.
View Article and Find Full Text PDFWorld J Gastrointest Surg
January 2025
Department of Minimally Invasive Digestive Surgery, Antoine-Béclère Hospital, Assistance Publique-Hôpitaux de ParisClamart 92140, Haute-Seine, France.
Anastomotic leakage (AL) is a significant complication following rectal cancer surgery, adversely affecting both quality of life and oncological outcomes. Recent advancements in artificial intelligence (AI), particularly machine learning and deep learning, offer promising avenues for predicting and preventing AL. These technologies can analyze extensive clinical datasets to identify preoperative and perioperative risk factors such as malnutrition, body composition, and radiological features.
View Article and Find Full Text PDFFront Artif Intell
January 2025
Department of Linguistics and Communication, University of Birmingham, Birmingham, United Kingdom.
In this article, we introduce a sociolinguistic perspective on language modeling. We claim that language models in general are inherently modeling , and we consider how this insight can inform the development and deployment of language models. We begin by presenting a technical definition of the concept of a variety of language as developed in sociolinguistics.
View Article and Find Full Text PDFPak J Med Sci
January 2025
Dr. Ali Mansoor, MBBS, FCPS, FRCR Department of Radiology, Ameer ud Din Medical College/Post Graduate Medical Institute/Lahore General Hospital, Lahore, Pakistan. Email:
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