AI Article Synopsis

  • Nine children aged 2 months to 13 years with renal hypertension were treated with captopril for 1.5 to 14 months, using doses between 1 and 5 mg/kg/day.
  • Captopril was effective in managing hypertension in kids with normal renal function and mild renal insufficiency.
  • However, the treatment was ineffective for children in end-stage renal disease when dialysis was not maintaining normal body water levels.

Article Abstract

Nine children aged 2 months to 13 (mean 6.6) years with renal hypertension were treated with captopril. The treatment lasted for 1.5 to 14 months. Maintenance doses ranged between 1 and 5 mg/kg/day. Good effect was achieved with captopril in children with normal renal function and in mild renal insufficiency. In patients with end-stage renal disease when dialysis failed to maintain normal body water captopril was ineffective.

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Source
http://dx.doi.org/10.3109/10641968609046604DOI Listing

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