Bacterial cancer therapy: A turning point for new paradigms.

Drug Discov Today

Department of Chemical Engineering, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada. Electronic address:

Published: August 2022

Cancer treatments have advanced considerably in recent years, appreciably enhancing the quality of life and survival of cancer patients. However, standard cancer treatments still have limitations that must be improved. In recent years, bacteria-based cancer therapy has gained much more attention owing to its unique properties that are unachievable with standard therapeutics. Bacteria species such as Salmonella, Clostridium, and Listeria have been shown to control tumor growth with improved prognosis in experimental animal models and clinical settings.

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http://dx.doi.org/10.1016/j.drudis.2022.03.007DOI Listing

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