The presented method of breast treatment, used in a total histologic study, allows one to avoid freasing microtome for large sections, hence, deformation of histologic structures. In cases, when breast consists mainly of fatty tissue, it is impossible to obtain histotopographic sections. The presented scheme of tissue treatment involving standard sledge microtome, acetone, thermostat heat provides 25-35 micron sections. The method can be widely used by pathologists for total histotopographic study of the organ.

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