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A short update on new approaches to celiac disease.
Acta Biomed
December 2022
department of Biology, faculty of Science, University Ibn Tofail, kenitra , Morocco .
Celiac disease is an autoimmune enteropathy of the small intestine, related to gluten intolerance occurring in genetically predisposed patients. Currently, the only available treatment is a lifelong gluten-free diet. However, the total avoidance of gluten is difficult and poses a challenge to patients, nutritionists and treating physicians.
View Article and Find Full Text PDFLifetime sexual violence exposure in women compromises systemic innate immune mediators associated with HIV pathogenesis: A cross-sectional analysis.
Womens Health (Lond)
May 2022
Department of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.
Objectives: Violence and HIV/AIDS syndemic highly prevalent among women impairs HIV prevention efforts. Prolonged exposure to violence results in physical trauma and psychological distress. Building on previous findings regarding genital immune dysregulation following sexual abuse exposure, we investigate here whether systemic changes occur as well.
View Article and Find Full Text PDFCorrection to: Elafin promotes tumour metastasis and attenuates the anti-metastatic effects of erlotinib via binding to EGFR in hepatocellular carcinoma.
J Exp Clin Cancer Res
March 2022
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China.
Elafin as a Predictive Biomarker of Acute Skin Graft--Host Disease After Haploidentical Stem Cell Transplantation Using Post-Transplant High-Dose Cyclophosphamide.
Front Immunol
June 2021
Department of Hematology, Gregorio Marañón General University Hospital, Madrid, Spain.
Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) has shown favorable results in the treatment of hematological malignancies. Despite the use of post-transplant cyclophosphamide (PTCy), graft host disease (GVHD) remains as one of the main complications in this setting. Since the skin appears affected in up to 80% of cases of acute GVHD (aGVHD), its prognosis and diagnosis are essential for the correct management of these patients.
View Article and Find Full Text PDFUnderstanding Solar Skin Elastosis-Cause and Treatment.
J Cosmet Sci
September 2018
BASF Beauty Care Solutions, Lyon 69007, France (S.P., N.B., C.N., V.D., V.A.).
Photoageing, also called actinic ageing, is the main cause of prematurely aged skin. Our expertise in elastic fibers has led us to discover a process triggered in response to ultraviolet (UV) light and which upsets the balance of elastin fibers: there is too much elastin and insufficient lysyl oxidase (LOXL1) enzyme to form functional elastic fibers. This imbalance then leads to an accumulation of nonfunctional elastin, which forms aggregates.
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