Objective: This study aimed to analyze the effects of transcutaneous electrical acupoint stimulation (TEAS) on the immune function in patients with pulmonary tuberculosis (PT) and the inflammatory response following one-lung ventilation surgery by comparing the levels of inflammatory mediators, such as tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and interleukin 8 (IL-8); T lymphocyte subsets, including CD3, CD4, CD8, and CD4/CD8 cells; and natural killer cells (NK cells).
Methods: We randomly divided 62 patients who underwent general anesthesia for thoracotomy into two groups: TEAS and sham TEAS. Patients in the TEAS group underwent bilateral acupoint electrical stimulation at the HouXi, ZhiGou, NeiGuan, and HeGu acupoints from 30 min before anesthesia induction until the end of surgery. TEAS was continuously maintained throughout the procedure with a dilatational wave at 2/100 Hz. Those in the sham TEAS group underwent the same management but without stimulation, and the anesthesia induction and maintenance methods were the same in both groups. Venous blood was drawn to monitor inflammatory mediators and lymphocyte subsets before anesthesia induction and 5 days after the surgery.
Results: There was no statistical difference in the general conditions between the two groups ( > 0.05). Before anesthesia induction, the levels of inflammatory factors (IL-6, IL-8, and TNF-α), lymphocyte subsets (CD3, CD4, and CD4/CD8), and NK cells did not statistically differ between the two groups ( > 0.05). Compared to the sham TEAS group, the levels of IL-6, IL-8, TNF-α, and CD8 were lower in the TEAS group, while those of CD3, CD4, CD4/CD8, and NK cells were higher; however, only the change in TNF-α was significant ( < 0.05).
Conclusion: TEAS at the HouXi, ZhiGou, NeiGuan, and HeGu acupoints at 2 Hz/100 Hz can reduce the inflammatory response during one-lung ventilation but has no significant effect on the immune function in patients with tuberculosis.
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http://dx.doi.org/10.1016/j.jctube.2022.100298 | DOI Listing |
Foods
January 2025
Graduate School of Horticulture, Chiba University, 648, Matsudo, Matsudo 271-8510, Japan.
In this study, the effects were explored of digestive enzymes and pH on the bioaccessibility of polyphenols, flavonoids, and antioxidant activities in Hojicha (roasted green tea, RT) infusions during simulated in vitro digestion. Roasting modifies its polyphenolic profile and reduces bitterness, making it a popular variation of green tea. In this study, RT was used for assessing how the roasting-induced changes influenced the tea's bioaccessibility and stability under digestive conditions.
View Article and Find Full Text PDFAm J Manag Care
January 2025
McGovern Medical School at UTHealth Houston, 4513 Teas St, Bellaire, TX 77401.
Objective: To examine the effect of physiologic insulin resensitization (PIR) on the cost of treating patients with diabetes and chronic kidney disease (CKD).
Study Design: The mean 1-year cost of treating 66 Medicare Advantage patients with diabetes and CKD who were receiving PIR was compared with that of treating 1301 Medicare Advantage patients with diabetes and CKD not receiving PIR. Differences in disease severity were compared using mean risk adjustment factor scores.
Pak J Pharm Sci
January 2025
Department of Food Science and Nutrition, Alkhurmah University College, Taif University, Taif, Saudi Arabia.
The purpose of the current study was to investigate the potential ameliorating murine reproductive effects of herbal tea extracts against bisphenol A-induced (BPA) cytotoxicity. A comparative study was applied among red, green and blue teas in mice groups. Samples were coded as RTE, GTE and BTE groups, respectively.
View Article and Find Full Text PDFBMJ Support Palliat Care
January 2025
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, Tianjin, China
Importance: Limb spasticity is a common issue among stroke patients. Transcutaneous electrical acupoint stimulation (TEAS) is recommended as an alternative therapy for managing upper limb spasticity after stroke; however, its potential effects and feasibility remain uncertain.
Objective: To investigate the potential effects and feasibility of TEAS on motor function in patients with upper limb spasticity after stroke.
PLoS One
January 2025
The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, China.
Background: Postoperative cognitive dysfunction (POCD) is associated with an increased risk of dementia and may lead to chronic neurodegeneration. The utilization of intraoperative Transcutaneous Electrical Acupoint Stimulation (TEAS) in conjunction with anesthesia is expected to become an effective preventive measure for POCD in clinical practice.
Methods: We conducted a comprehensive literature review focusing on the use of TEAS in the prevention of POCD during surgical anesthesia.
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