Spatiotemporal pulse shaping provides control over the trajectory and range of an intensity peak. While this control can enhance laser-based applications, the optical configurations required for shaping the pulse can constrain the transverse or temporal profile, duration, or orbital angular momentum (OAM). Here we present a novel technique for spatiotemporal control that mitigates these constraints by using a "stencil" pulse to spatiotemporally structure a second, primary pulse through cross-phase modulation (XPM) in a Kerr lens. The temporally shaped stencil pulse induces a time-dependent focusing phase within the primary pulse. This technique, the "flying focus X," allows the primary pulse to have any profile or OAM, expanding the flexibility of spatiotemporal pulse shaping for laser-based applications. As an example, simulations show that the flying focus X can deliver an arbitrary-velocity, variable-duration intensity peak with OAM over distances much longer than a Rayleigh range.
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http://dx.doi.org/10.1364/OE.451123 | DOI Listing |
Cureus
November 2024
Internal Medicine, Olabisi Onabanjo University, Ago-Iwoye, NGA.
Background Combining left atrial appendage closure with catheter ablation (LAACCA) has been proposed as a potential approach to improving outcomes by simultaneously addressing arrhythmia and reducing stroke risk. This study compares the in-hospital outcomes of LAACCA vs. catheter ablation (CA) alone for atrial fibrillation (AFib) in patients with heart failure with reduced ejection fraction (HFrEF).
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November 2024
Pediatrics, Kagoshima University Hospital, Kagoshima, JPN.
Background Children with Down syndrome (DS) often have hypoplastic kidneys and urinary tract malformations that increase their renal dysfunction risk. They also have a higher congenital heart disease (CHD) rate, requiring cardiac surgery during infancy. Renal dysfunction in such patients may be associated with the development of cardiac surgery-associated acute kidney injury (CS-AKI), but this remains unclear.
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November 2024
Cardiovascular Medicine, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Background With the rising number of children with congenital heart disease (CHD) reaching adulthood, surgical intervention has become a critical aspect of their long-term management. This study presents a six-year overview of early postoperative outcomes and mortality in CHD surgeries at a single center, underscoring advancements and challenges in treating this complex population. Objective As more children with CHD grow into adulthood, we are gaining critical insights from our extensive experience in performing cardiac surgery for this population.
View Article and Find Full Text PDFJ Gastrointestin Liver Dis
December 2024
Department of Medical and Surgical Sciences, IRCCS St. Orsola Polyclinic, University of Bologna, Bologna; Department of Cardiovascular Medicine Unit, Heart, Chest and Vascular, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Background And Aims: Bacterial resistance toward the most used antibiotics is increasing in Helicobacter pylori (H. pylori) strains worldwide. The emergence of multidrug resistance significantly affects the efficacy of standard therapy regimens.
View Article and Find Full Text PDFTrials
December 2024
Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Background: Intermediate-high risk pulmonary embolism (PE) carries a significant risk of hemodynamic deterioration or death. Treatment should balance efficacy in reducing clot burden with the risk of complications, particularly bleeding. Previous studies on high-dose, short-term thrombolysis with alteplase (rtPA) showed a reduced risk of hemodynamic deterioration but no change in mortality and increased bleeding complications.
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