AI Article Synopsis
- * Technetium-99m dimercaptosuccinic acid (Tc-DMSA) scans are the main method for detecting kidney scarring resulting from UTIs.
- * In a study involving five girls with confirmed kidney issues after a UTI, out of 20 kidneys scanned, 10 showed scarring, but only 7 had contour abnormalities, suggesting that contour issues are not essential for diagnosing scarring.
Article Abstract
Urinary tract infections in children can lead to permanent renal scarring in approximately 15% of cases. Technetium-99m (Tc)-dimercaptosuccinic acid (DMSA) scintigraphy is the gold standard for identifying renal scarring. Using data and scans from children enrolled at our center in a 2-year prospective clinical trial (RIVUR study), we included children with radiologically confirmed pyelonephritis who exhibited renal scarring on their 1 and/or 2-year follow-up scans and asked 3 blinded pediatric nuclear medicine physicians to reexamine the renal contours in these scans. Five girls met all eligibility criteria (each had two late Tc-DMSA scans 1 and 2 years after index UTI). Of the 20 kidneys imaged, 10 exhibited renal scarring and of these, 7 exhibited renal contour abnormalities. These findings suggest that the presence of abnormalities of the renal contour is not necessary for diagnosis of renal scarring.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918400 | PMC |
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