There is growing evidence that visual attention can be guided by selection history. One example of this is intertrial location priming, whereby attention is attracted to the target location from the previous trial. Most previous demonstrations of location priming have relied on manual response time effects whereby search is speeded when the target location repeats from the previous trial. However, these latency-based effects have recently been challenged as being due to response facilitation that occurs after the target has been found, rather than an attentional bias toward the previous target location. To resolve this, the current study used a probe paradigm to assess whether covert attention is biased to the previous-trial target location. On search trials, participants searched for a specific target shape amongst distractor shapes and made a speeded response to the location of a dot inside the target. On probe trials, letters briefly appeared at each search location and after a delay, participants were asked to report as many letters as possible. Probe report accuracy was used to assess the likelihood that a given location was attended. Three experiments indicated that probe report accuracy was greatly improved for letters at the previous-trial target location compared with baseline levels. Importantly, this occurred even when strong attentional guidance to the target was encouraged and even when a nontarget stimulus appeared at the primed location. Altogether, the results suggest that covert attention is strongly attracted to the previous target location during visual search.
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http://dx.doi.org/10.3758/s13414-022-02462-x | DOI Listing |
J Neurosurg
December 2024
Departments of1Neurosurgery.
Objective: Periventricular anastomosis (PA), a recently recognized cause of hemorrhage in moyamoya disease, is reducible after bypass surgery. The timing of the reduction, however, remains poorly understood. The objectives of the present study were to demonstrate radiological reduction of PA occurring within 48 hours after surgery and to identify factors associated with reduction.
View Article and Find Full Text PDFJ Chem Inf Model
December 2024
Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland Baltimore, Baltimore, Maryland 21201, United States.
Drug efficacy often correlates better with dissociation kinetics than binding affinity alone. To study binding kinetics computationally, it is necessary to identify all of the possible ligand dissociation pathways. The site identification by ligand competitive saturation (SILCS) method involves the precomputation of a set of maps (FragMaps), which describe the free energy landscapes of typical chemical functionalities in and around a target protein or RNA.
View Article and Find Full Text PDFEnviron Health Perspect
December 2024
Public and Occupational Health, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.
Background: Climate change is the 21st century's biggest global health threat, endangering health care systems worldwide. Health care systems, and hospital care in particular, are also major contributors to greenhouse gas emissions.
Objectives: This study used a systematic search and screening process to review the carbon footprint of hospital services and care pathways, exploring key contributing factors and outlining the rationale for chosen services and care pathways in the studies.
Inflammation
December 2024
Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Intermittent fasting (IF) has been shown to ameliorate inflammation including DSS-induced colitis. It is well known that autophagy can limit inflammation and TFEB is a master transcriptional factor that regulates the processes of autophagy. However, whether TFEB is involved in the regulation of IF-mediated amelioration of inflammation and its mechanism remained unclear.
View Article and Find Full Text PDFVet Sci
December 2024
College of Veterinary Medicine and Bio-Safety Research Institute, Jeonbuk National University, Iksan Campus, Gobong-ro 79, Iksan 54596, Republic of Korea.
Bacterial skin infections, particularly pyoderma and otitis externa, are widespread in dogs, primarily caused by and species. This study evaluates the prevalence and types of bacterial pathogens in affected dogs in South Korea using a meta-analytical approach. Following the PRISMA guidelines, five electronic databases were searched for relevant studies published between 1990 and 2024.
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