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Association between serum bicarbonate and 28-day mortality in critically ill patients with infective endocarditis: a cohort study from MIMIC-IV.
Sci Rep
January 2025
Department of Infectious Disease, Beijing Luhe Hospital, Capital Medical University, Beijing, 101149, China.
Article Synopsis
- The study examined the relationship between serum bicarbonate levels and 28-day mortality in critically ill patients with infective endocarditis using data from the MIMIC-IV database.
- Patients with higher serum bicarbonate levels upon ICU admission showed significantly lower mortality rates, suggesting that bicarbonate levels can be a potential prognostic marker.
- The findings indicate that monitoring bicarbonate levels could help assess risk and guide the clinical management of patients with infective endocarditis.
Brucella Endocarditis: A Case Series.
Cureus
December 2024
Internal Medicine, Sher-I-Kashmir Institute Of Medical Sciences, Srinagar, IND.
Brucellosis is one of the most common zoonotic infections present worldwide. It usually presents as a febrile illness but can affect multiple organs of the body. Although cardiac involvement in brucellosis is rare, it is a fatal organ involvement.
View Article and Find Full Text PDFPrognosis and Treatment Effectiveness of Austrian Syndrome: A Case Report and Systematic Review.
Cureus
December 2024
Neurosurgery, Nagoya University Hospital, Nagoya, JPN.
Austrian syndrome is a rare triad of meningitis, pneumonia, and endocarditis caused by . It is associated with high morbidity and mortality rates. Most reports describe pneumonia as the initial illness, followed by multi-organ involvement.
View Article and Find Full Text PDFThe expanding role of 16s ribosomal RNA PCR in the management of patients with infective endocarditis undergoing cardiac surgery.
Front Cardiovasc Med
December 2024
Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Background: Aetiological diagnosis and targeted antibiotic therapy are essential to improve the prognosis of patients with infective endocarditis. Molecular tests on blood have been reported to be effective in identifying the causative organism and are recommended when blood cultures are negative. The role of molecular tests on the surgically excised valve is still unclear and needs further investigation.
View Article and Find Full Text PDFManaging Recurrent Endocarditis in Substance Use Disorder: The Role of Civil Commitment and Comprehensive Care.
Am J Case Rep
January 2025
Department of Behavioral Medicine and Psychiatry, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.
BACKGROUND The incidence of drug-induced infectious endocarditis is rapidly rising in the United States. Healthcare providers face different challenges in the management of infectious endocarditis in persons who inject drugs, including addiction relapse, non-compliance with treatment, and the associated social stigma. These factors collectively complicate the management of drug-induced endocarditis, requiring comprehensive strategies that address both the medical condition and the underlying substance use disorder, as well as socio-behavioral aspects of patient care.
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