The mechanism of chromosome biorientation during mitotic spindle assembly remains a century-old mystery. In contrast to the stochastic models that have dominated the field for decades, a new study now proposes that chromosome biorientation is instead deterministic and driven by microtubule self-organization at kinetochores.
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| http://dx.doi.org/10.1016/j.cub.2022.02.003 | DOI Listing |
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