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| http://dx.doi.org/10.1007/s00247-022-05342-6 | DOI Listing |
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The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers.
J Cancer Res Clin Oncol
January 2025
Sarcoma Unit, Department of Surgery, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Purpose: The management of soft tissue sarcoma (STS) at reference centers with specialized multidisciplinary tumor boards (MTB) improves patient survival. The German Cancer Society (DKG) certifies sarcoma centers in German-speaking countries, promoting high standards of care. This study investigated the variability in treatment recommendations for localized STS across different German-speaking tertiary sarcoma centers.
View Article and Find Full Text PDFFeasibility of AI as first reader in the 4-IN-THE-LUNG-RUN lung cancer screening trial: impact on negative-misclassifications and clinical referral rate.
Eur J Cancer
December 2024
Institute for Diagnostic Accuracy, Groningen, the Netherlands; Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:
Background: Lung cancer screening (LCS) with low-dose CT (LDCT) reduces lung-cancer-related mortality in high-risk individuals. AI can potentially reduce radiologist workload as first-read-filter by ruling-out negative cases. The feasibility of AI as first reader was evaluated in the European 4-IN-THE-LUNG-RUN (4ITLR) trial, comparing its negative-misclassifications (NMs) to those of radiologists and the impact on referral rates.
View Article and Find Full Text PDFGeographic variation of recorded neurodevelopmental disorders in children and adults.
Dan Med J
November 2024
NCRR - National Centre for Register-based Research, School of Business and Social Sciences, Aarhus University.
Introduction: While diagnosis rates of autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD) vary within countries at a large-scale municipal level, small neighbourhood geographic variation remains understudied. In this nationwide study, we describe the rates of ASD and ADHD diagnoses in children and adults by geographical data zones of approximately 2,500 residents across Denmark.
Methods: We included a population of children born from 1993 through 2020 and an adult population born from 1977 through 2003.
Rate and yield of imaging for acute pyelonephritis in the emergency department: A retrospective cohort study.
Emerg Med Australas
February 2025
Emergency Service, Alfred Health, Melbourne, Victoria, Australia.
Objectives: The role of imaging in acute pyelonephritis (APN) in the ED is poorly understood, with variability among clinical guidelines for when patients should be imaged, and the modality of imaging. The objective of this study was to identify the proportion of patients with APN being imaged, the proportion abnormal findings, and the association between abnormal imaging and discharge disposition.
Methods: A single-centre retrospective review of patients with a discharge diagnosis of APN at an adult tertiary referral hospital over a 5-year period (2018-2022) was conducted.
Clinical impact of pre-determined guideline selection for the diagnosis of fibrotic hypersensitivity pneumonitis.
Respir Med
December 2024
Pulmonology Department, Unidade Local de Saúde de São João, Alameda Professor Hernani Monteiro, 4200-319, Porto, Portugal; Faculty of Medicine, University of Porto, Alameda Professor Hernani Monteiro, 4200-319, Porto, Portugal.
Introduction And Objectives: International guidelines for the diagnosis of Hypersensitivity Pneumonitis (HP) have improved the diagnostic standardization of this heterogeneous interstitial lung disease. Our goal was to determine how the final multidisciplinary discussion confidence level for suspected fibrotic HP (fHP) can be impacted by the application of different guidelines validated in this context.
Materials And Methods: Retrospective study including patients submitted to transbronchial lung cryobiopsy (TBLC) with a final multidisciplinary meeting diagnosis of fHP.
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