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Two lanostane triterpenoids with -glucosidase inhibitory activity from the fruiting bodies of . | LitMetric

A new oxygenated lanostane-type triterpenoid, 20,24-epoxy-lanosta-7,9(11)-dien-3,15,25,26-tetraol (), together with three known compounds (-) were isolated from the fruiting bodies of . Extensive NMR spectrometry and HRESIMS analysis, as well as NMR and ECD calculations elucidated the structure of the new compound. 27-nor-3-hydroxylanosta-7,9(11),23-trien-25-one () showed superior -glucosidase inhibitory activity with IC value of 122.1 μM to that of positive control acarbose (304.6 μM).

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Source
http://dx.doi.org/10.1080/14786419.2022.2050911DOI Listing

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