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Dementia Care Practice.
Alzheimers Dement
December 2024
Odessa National Maritime University, Odessa, Ukraine.
Background: Patients with Alzheimer's disease due to the peculiarities of this disease do not report constipation.
Method: In a study of 11 women with Alzheimer's disease, aged 70-75 years, we found that all of them had a tendency towards constipation. We divided the patients into two groups: a control group of 6 women who received help when they complained of constipation symptoms and an experimental group of 5 female patients who were routinely assessed by caregivers on their fecal status using the Bristol Scale.
Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye: application to tablet analysis.
BMC Chem
January 2025
Department of Pharmaceutical Chemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Novel, «green» and simple visible spectrophotometric procedures for the determination of six dihydropyridines CCBs (amlodipine besylate (AML), lacidipine (LAC), levamlodipine besylate (LAML), nifedipine (NIF), nimodipine (NIM) and nitrendipine (NIT)) through derivatization with the sulfophthalein dye bromophenol blue (BPB) have been developed. The optimal parameters for CCBs spectrophotometric analysis via complex formation using BPB were as follows: detection wavelength-596 nm, reaction time-5 min, ratio of reacting components-1:1, operating temperature-25 ± 2 °C. The concentration was linearly proportional to absorbance values in the range of 3.
View Article and Find Full Text PDFChronic pain lasting more than three months or persisting after normal healing is a significant global health issue. In a healthcare system, it is crucial to ensure proper chronic pain management. Traditional pharmacological and non-pharmacological pain management techniques may not fully meet the requirements of physicians regarding effectiveness and safety.
View Article and Find Full Text PDFIn recent years, non-invasive screening methods for diagnosing various human conditions, including those corresponding to biological age, have attracted great interest, one of the sources for non-invasive research of which is oral fluid.
View Article and Find Full Text PDFPrevalence and management of hypertension in Turner syndrome: data from the International Turner Syndrome (I-TS) registry.
Endocr Connect
January 2025
H Turner, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford Centre for Diabetes Endocrinology and Metabolism, Oxford, United Kingdom of Great Britain and Northern Ireland.
Introduction: Cardiovascular disease is the commonest cause of death in Turner syndrome (TS) for which, arterial hypertension has a direct influence and is a key modifiable risk factor.
Objective: To investigate the prevalence and patterns of hypertension diagnosis and management in adult patients with TS who are registered in a large international multicentre database (TS-HTN study).
Methods: Retrospective multi-centre observational study of patients aged ≥18 years, included in the I-TS (International-TS) registry (2020-2022) utilising registry and participating centre collected data.
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