AI Article Synopsis
- This study investigates the link between Pressure Pain Threshold (PPT) and knee function in patients with advanced Knee Osteoarthritis (KOA) undergoing total knee arthroplasty.
- Higher PPT scores are associated with better self-reported knee function and improved performance in the 6-minute walk test.
- Despite these findings, PPT measures only explain a small portion of the variance in knee function, suggesting limitations in understanding pain mechanisms related to knee function post-surgery.
Article Abstract
Background: Studies in Knee Osteoarthritis (KOA) have shown lowered Pressure Pain Threshold (PPT) values compared to healthy controls potentially signifying mechanical hypersensitivity, although the relevance of these findings to knee function remains unclear.
Objective: This study further explores the relationship between PPT measures and knee function (self-reported, physical) in individuals undergoing total knee arthroplasty for advanced KOA.
Design: Cross-sectional observational study.
Methods: PPT's were recorded both local to the affected knee and at a remote site (deltoid) in 79 individuals with advanced KOA. Participants also completed self-report (Knee Society Score - functional sub-score) and physical (6-min walk test distance)) measures of knee function, as well as measures of pain-related psychological distress. Hierarchical linear regression models evaluated the relationship between the measures of function (self-report and physical measures modelled separately), PPT measures (local and remote), while accounting for demographic and psychological distress measures.
Results: Higher knee PPT scores were independently associated with higher self-reported knee function (β 0.33, p < 0.02) and higher 6-min walk test distance (β 0.41, p < 0.01), although pain self-efficacy (β 0.33, p < 0.01) was also a significant variable in both models. Nearly identical findings were evident for PPT's measured at the deltoid. Overall PPT's could only explain a modest portion of variance (adjusted R = 0.15 to 0.17) in the functional measures.
Conclusions: PPT measures may be limited in their capacity to distinguish the impact of peripheral and central pain mechanisms on knee function in individuals undergoing total knee arthroplasty for advanced KOA.
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| http://dx.doi.org/10.1016/j.msksp.2022.102542 | DOI Listing |
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