Gravity-induced ischemia in the brain-and prone positioning for COVID-19 patients breathing spontaneously.

Acute Crit Care

Anatomic Pathology, Lino Rossi Research Center, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

Published: February 2022

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918714PMC
http://dx.doi.org/10.4266/acc.2021.01739DOI Listing

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Gravity-induced loss of consciousness (G-LOC) is a major threat to fighter pilots and may result in fatal accidents. The brain has a period of 5-6 s from the onset of high +G exposure, called the functional buffer period, during which transient ischemia is tolerated without loss of consciousness. We tried to establish a method for predicting G-LOC within the functional buffer period by using machine learning.

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Gravity-induced ischemia in the brain-and prone positioning for COVID-19 patients breathing spontaneously.

Acute Crit Care

February 2022

Anatomic Pathology, Lino Rossi Research Center, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

View Article and Find Full Text PDF

Cerebral hemodynamics and brain oxygen changes related to gravity-induced loss of consciousness in rhesus monkeys.

Neurosci Lett

February 2003

Institut de Médecine Aérospatiale du Service de Santé des Armées, Département Physiologie, BP 73, 91223 Brétigny-sur-Orge Cedex, France.

The aim of the present experiment was to study the influence of +Gz acceleration (head-to-foot inertial forces) onset on cerebral oxygenation changes (cerebral oxy- and deoxy-hemoglobin) and cerebral blood volume (CBV) in order to evaluate the role of cerebral hypoxemia and ischemia in the appearance of +Gz-induced loss of consciousness (G-LOC). We used five rhesus monkeys which were equipped with near infrared spectroscopy optodes fixed onto the parietooccipital cranial bone. G-LOC (isoelectric electrocorticogram) was detected with silver balls electrodes in contact with the dura matter.

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