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Workflow improvements from automated large vessel occlusion detection algorithms are dependent on care team engagement.
J Neurointerv Surg
January 2025
Department of Neurology, UTHealth Houston McGovern Medical School, Houston, Texas, USA
Background: Automated machine learning (ML)-based large vessel occlusion (LVO) detection algorithms have been shown to improve in-hospital workflow metrics including door-to-groin time (DTG). The degree to which care team engagement and interaction are required for these benefits remains incompletely characterized.
Methods: This analysis was conducted as a pre-planned post-hoc analysis of a randomized prospective clinical trial.
Soil permeability shaping ARGs patterns by affecting soil available nutrients in paddy fields.
Environ Pollut
January 2025
Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, Ministry of Education, College of Environment, Hohai University, Nanjing, Jiangsu 210098, P.R. China.
Though the evidence for soil property could influence the antibiotic resistance genes (ARGs) profiles is mounting, studies regarding the effect of soil permeability on soil ARGs patterns are still ignored. This study investigated the dynamic distribution of ARGs in paddy fields with different soil permeability over various rice growing stages, as well as revealed the abiotic and biotic factors that shaping ARGs profiles. Results indicate that soil with high permeability improved the ARGs abundance through elevating the available nutrients in the soil.
View Article and Find Full Text PDFA flagella-dependent jumbo phage controls rice seedling rot and steers toward reduced virulence in rice seedlings.
mBio
January 2025
Department of Biological Sciences, College of Natural & Applied Sciences, University of Alberta, Edmonton, Alberta, Canada.
Bacteriophages (phages) are being investigated as potential biocontrol agents for the suppression of bacterial diseases in cultivated crops. Jumbo bacteriophages, which possess genomic DNA larger than 200 kbp, generally have a broader host range than other phages and therefore would be useful as biocontrol agents against a wide range of bacterial strains. Thus, the characterization of novel jumbo phages specific for agricultural pathogens would be of importance for the development of phage biocontrol strategies.
View Article and Find Full Text PDFInvesting in equitable healthy aging: Why Africa must reform social pension schemes to improve Alzheimer's disease and dementia outcomes.
Alzheimers Dement
January 2025
Brain and Mind Institute, Aga Khan University, Nairobi, Kenya.
The eligibility criteria for social pension schemes in Africa hinder equitable and healthy aging. In 2019, women in 14 sub-Saharan African countries had an average life expectancy of 67 years but a healthy life expectancy of only 57 years, leaving them 5 years in poor health before receiving a pension at age 62. Men had a similar situation-a life expectancy of 62 years and a healthy life expectancy of 53 years, spending 10 years in poor health before becoming eligible for pensions at age 63.
View Article and Find Full Text PDFGene-ius at work: Hemophilia B treatment enters a new era.
Am J Health Syst Pharm
January 2025
Department of Pharmacy Practice, Auburn University Harrison College of Pharmacy, Auburn, AL, USA.
Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.
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