Purpose: To report the surgical effects of a combination treatment comprising the lateral rectus belly transposition (LRBT) procedure, without muscle splitting or disinsertion, and ipsilateral antagonist recession for vertical rectus palsy.
Methods: The medical records of consecutive patients who underwent the LRBT procedure between 2017 and 2020 were reviewed. Preoperative and postoperative deviation in primary position, preoperative and postoperative scale of duction of the palsied muscle, any induced horizontal or torsional deviation, and other complications were collected.
Results: Thirteen patients were identified: 10 with inferior rectus palsy and 3 with superior rectus palsy. The mean postoperative follow-up time was 20.4 ± 8.0 months. Eleven patients (84.6%) underwent simultaneous recession of the ipsilateral antagonist muscle of the palsied vertical rectus. After surgery, the mean vertical deviation improved from 31.4 ± 16.4 to 1.9 ± 3.6 prism diopters (PD) ( < .001). The mean vertical duction limitation of the palsied muscle improved from -2.7 ± 0.6 to -0.6 ± 0.5 ( = .001). In one patient, the scleral fixation suture was removed due to continuous reverse vertical diplopia. The total success rate was 76.9%. No induced horizontal deviation was noted. Anterior segment ischemia or other severe surgical complications did not occur.
Conclusions: The LRBT procedure can be effective, safe, and reversible in patients with vertical rectus palsy. It allows for the option of simultaneous ipsilateral antagonist recession, and it is especially valuable in patients whose vertical duction deficiency is worse in abduction but mild in adduction. .
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http://dx.doi.org/10.3928/01913913-20220211-02 | DOI Listing |
Hypertens Res
January 2025
Department of Cardiology, Department of Clinical Medicine, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Superselective adrenal artery embolization (SAAE) has increasingly emerged as an alternative treatment for primary aldosteronism (PA) patients who either unwilling or unable to undergo surgical adrenalectomy, and cannot tolerate or refuse to mineralocorticoid receptor antagonists (MRAs). Although SAAE has been applied in PA treatment for over two decades, its safety and efficacy are still uncertain due to absence of multi-center, randomized controlled trials, hindering its widespread clinical adoption. Currently, only a few centers could perform this procedure proficiently, leading to variability in technical protocols and clinical outcomes across different institutions.
View Article and Find Full Text PDFCell Tissue Res
January 2025
Research Institute for Electronic Science, Hokkaido University, Sapporo, 060-0812, Japan.
The smoky brown cockroach, Periplaneta fuliginosa, is a peridomestic pest inhabiting broad regions of the world from temperate to subtropical zones. In common with other related species such as the American cockroach, Periplaneta americana, female-emitted sex pheromone components, named periplanones, are known to be key volatiles that elicit long-range attraction and courtship rituals in males. How periplanones are processed in the nervous system has been entirely unexplored in P.
View Article and Find Full Text PDFMed Sci Sports Exerc
December 2024
Centre for Human Performance, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, AUSTRALIA.
Introduction: We tested the hypothesis that muscle damage protection effect would be induced by its antagonist muscle eccentric exercise.
Methods: Sedentary young (20-28y) men were randomly assigned into six groups; three groups each for arm or leg exercise group (n = 12/group). One group performed two bouts of 30 maximal eccentric contractions (30MaxEC) of the elbow flexors (EF) or 60 maximal eccentric contractions (60MaxEC) of the knee flexors (KF) using a different arm (contra-EF-EF) or leg (contra-KF-KF) between bouts.
J Cell Mol Med
November 2024
Department of Anesthesiology, Panzhihua Central Hospital, Panzhihua, Sichuan, China.
Sinomenine (SIN), a bioactive isoquinoline alkaloid extracted from the roots and stems of Sinomenium acutum, is efficacious against various chronic pain conditions. Inhibition of microglial activation at the spinal level contributes to the analgesic effects of SIN. Microglial activation in the spinal dorsal horn is key to sensitising neuropathic pain.
View Article and Find Full Text PDFPeerJ
November 2024
Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Neuronal apoptosis, oxidative stress, and ferroptosis play a crucial role in the progression of secondary brain injury following intracerebral hemorrhage (ICH). Although studies have highlighted the important functions of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) in various experimental models, its precise role and mechanism in ICH remain unclear. In this study, we investigated the effects of DNA-PKcs on N2A cells under a hemin-induced hemorrhagic state and a rat model of collagenase-induced ICH .
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