Sheep pox is a highly contagious disease causing significant economic losses on livestock farms, especially among young animals. Epidemiological analysis of retrospective data on sheep pox surveillance over ten years revealed the endemicity of the disease in Tunisia. Temporally, the prevalence of infected farms increased during the last five years analysed (2013-2017), despite control measures for the disease, which are based essentially on vaccination. Analysis of the seasonality of infection showed that most outbreaks occurred in autumn and winter. The geographical distribution and spatial analyses classified the governorate of Sidi Bouzid as the area most affected by sheep pox duringthe period of study. It was observed that vaccination coverage decreasedbelow the recommended value (80%) in the last four years (2013-2016).
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http://dx.doi.org/10.20506/rst.39.3.3186 | DOI Listing |
Virology
December 2024
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, PR China. Electronic address:
Capripoxviruses (CaPVs), such as lumpy skin disease, sheep pox, and goat pox, cause significant production and economic losses and are major constraints to the growth of livestock production in endemic areas. Understanding the pathogenic mechanism of CaPVs and their translation into clinical applications depends on the availability of a suitable cell line. In this study, we used a lentiviral packaging system to establish an immortalized hTERT-bOEC cell line by ectopic introduction of human telomerase reverse transcriptase (hTERT).
View Article and Find Full Text PDFFront Vet Sci
November 2024
Key Laboratory of Animal Medicine of Sichuan Province, College of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Introduction: Monkeypox virus (MPXV) hosts are of multiple species, with a risk of cross-species transmission. This phenomenon poses a threat to unreported affected domestic animals and increases the risk to human public health. Clinical diagnostics continue to face challenges regarding specificity among poxviruses.
View Article and Find Full Text PDFAccess Microbiol
October 2024
The Pirbright Institute, Ash Road, Pirbright, Surrey, UK.
Multiple transboundary animal diseases (TADs) circulate in Plateau State, Nigeria, where livestock keeping is common and contributes to both the physical and socio-economic well-being of a large proportion of the population. In this study, we explored the potential for environmental sampling to detect viruses causing TADs circulating in the region. Electrostatic dust cloths were used to swab areas of the environment likely to have contact with secretions and excretions from infected animals.
View Article and Find Full Text PDFVirology
December 2024
College of Life Science and Technology, Xinjiang University, Urumqi, 830017, China; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, Urumqi, 830017, China.
The members of the miR-29 family play an important role in the process of viral infection. The sheep pox epidemic has hindered the development of the livestock industry worldwide. The aim of this study was to analyze the action mechanism of miR-29a during sheep pox virus (SPPV) infection.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2024
China Institute of Veterinary Drug Control, Beijing, China.
P32 protein serves as a crucial structural component of Goat pox virus (GTPV), which causes a highly virulent infectious disease in sheep and goats. Despite the fact that P32 has been widely expressed in the previous studies, it is difficult to obtain recombinant P32 efficiently. This study aimed to achieve soluble expression of P32 recombinant protein and to develop its specific monoclonal antibody.
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