AI Article Synopsis
- The text discusses the growing field of systemic treatment options for advanced thyroid cancer, highlighting its multidisciplinary nature and evidence-based approaches.
- An expert panel conducted a comprehensive literature review to create best practice statements and assess consensus using the modified Delphi method.
- Key findings include a molecular understanding of thyroid cancer, defined characteristics of advanced disease, and 20 statements on management, molecular evaluation, and targeted treatments.
Article Abstract
Background: The development of systemic treatment options leveraging the molecular landscape of advanced thyroid cancer is a burgeoning field. This is a multidisciplinary evidence-based statement on the definition of advanced thyroid cancer and its targeted systemic treatment.
Methods: An expert panel was assembled, a literature review was conducted, and best practice statements were developed. The modified Delphi method was applied to assess the degree of consensus for the statements developed by the author panel.
Results: A review of the current understanding of thyroid oncogenesis at a molecular level is presented and characteristics of advanced thyroid cancer are defined. Twenty statements in topics including the multidisciplinary management, molecular evaluation, and targeted systemic treatment of advanced thyroid cancer are provided.
Conclusions: With the growth in targeted treatment options for thyroid cancer, a consensus definition of advanced disease and statements regarding the utility of molecular testing and available targeted systemic therapy is warranted.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332138 | PMC |
| http://dx.doi.org/10.1002/hed.27025 | DOI Listing |
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