AI Article Synopsis
- Turner syndrome (TS) results from the missing part or all of an X chromosome in females, affecting 25-50 out of every 100,000 live births.
- The main health issue for those with TS is primary ovarian insufficiency (POI), which leads to lower estrogen levels and infertility.
- This review outlines care recommendations for adolescents and young adults with TS, emphasizing POI management, hormone replacement therapy, fertility preservation, and considerations for pregnancy.
Article Abstract
Turner syndrome (TS) is caused by the absence of a part or whole X chromosome in a phenotypic female and has an estimated prevalence of 25-50/100,000 live-born females. The primary gynecologic manifestation of TS is primary ovarian insufficiency (POI), and the resulting hypoestrogenism and infertility are experienced by most individuals with TS. In this review, we summarize the recommendations for the care of adolescents and young adults with TS, with a focus on primary ovarian insufficiency in TS, hormone replacement therapy, fertility preservation, and pregnancy in TS.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288983 | PMC |
| http://dx.doi.org/10.1016/j.jpag.2022.02.002 | DOI Listing |
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