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Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences. | LitMetric

Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences.

Int J Mol Sci

Institut de Recherche sur les Maladies Virales et Hepatiques UMR_S1110, Université de Strasbourg, Inserm, F-67000 Strasbourg, France.

Published: March 2022

AI Article Synopsis

Article Abstract

Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein-host interactions, the rapid technological development of -omics and bioinformatics has allowed highlighting the important role of signaling networks in viral pathogenesis. In this review, we provide an integrated look on the three major viruses associated with chronic viral hepatitis in patients, summarizing similarities and differences in virus-induced cellular signaling relevant to the viral life cycles and liver disease progression.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911453PMC
http://dx.doi.org/10.3390/ijms23052787DOI Listing

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