AI Article Synopsis
- A new sensor system called RFFS was developed to detect the antibiotic ciprofloxacin (CIP) in water using CdTe quantum dots (QDs) modified with specific compounds.
- Preliminary findings showed that CIP significantly reduced the fluorescence from the QDs, enabling the sensor to effectively measure CIP concentrations from 0 to 45 μM, with a detection limit of 0.90 μM.
- The study also explored how this fluorescence quenching occurred through a process called photoinduced electron transfer (PET), demonstrating the sensor's ability to resist interference from similar substances.
Article Abstract
A ratiometric fluorescence fiber-optical sensor system (RFFS) merging a Y-type optical fiber spectrometer and CdTe QDs composite functionalized with glutathione and mercaptopropionic acid (GMPA@CdTe-QDs) for highly selective and on-site detection of ciprofloxacin (CIP) in environmental water samples was designed. Our preliminary results suggested that the red fluorescence of the synthesized GMPA@CdTe-QDs was effectively quenched by CIP. Based on this, the RFFS/GMPA@CdTe-QDs system was successfully fabricated and used for highly selective and rapid detection of CIP on site in the concentration range from 0 to 45 μM with the detection limit of 0.90 μM. The established method exhibited good interference resistance to the analogues of CIP and provided a great potential platform for real-time detection of CIP residues in environmental water. In addition, the fluorescence quenching mechanism of GMPA@CdTe-QDs by CIP was also investigated by means of temperature effect, fluorescence lifetime, ultraviolet (UV) visible absorption, and fluorescent spectra. Our results suggested clearly that the red fluorescence of GMPA@CdTe-QDs was quenched by CIP via the photoinduced electron-transfer (PET) mode.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912570 | PMC |
| http://dx.doi.org/10.3390/nano12050829 | DOI Listing |
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