AI Article Synopsis
- The essential oil (EO) from myrtle, rich in compounds like myrtenyl acetate and linalool, was microencapsulated using maltodextrin through emulsification and spray-drying, achieving specific yield and efficiency rates.
- The microencapsulated form, named MMEO, demonstrated significant gastroprotective effects in Wistar rats by reducing gastric lesions and acidity in an ethanol/HCl-induced ulcer model.
- MMEO also showed strong anti-inflammatory properties, helping maintain antioxidant enzyme activity and suggesting that its protective effects stem from a combination of its anti-inflammatory and antioxidant actions.
Article Abstract
L. essential oil (EO), mainly composed of myrtenyl acetate (30.6%), linalool (14.9%), α-pinene (11.10%) and 1,8-cineole or eucalyptol (9.9%), was microencapsulated with maltodextrin by emulsification and spray-drying, reaching a yield and efficiency of 43.7 and 48.7%, respectively. The microencapsulated myrtle EO (MMEO) was then evaluated regarding its gastroprotective activity in a model of ethanol/HCl-induced acute gastric ulcer in Wistar rats. Pretreatment with MMEO induced a remarkable inhibition of gastric lesions and acidity, correlated to high healing and protection percentages. Moreover, it exerted a potent anti-inflammatory effect on the gastric mucosa, counteracting EtOH-induced gastric lipoperoxidation and preventing the depletion of the antioxidant enzyme activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). Taken together, the gastroprotective action of encapsulated MMEO may be multi-factorial, and ascribable, at least in parts, to its anti-inflammatory and antioxidant properties.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911731 | PMC |
| http://dx.doi.org/10.3390/molecules27051566 | DOI Listing |
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