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Improving spleen segmentation in ultrasound images using a hybrid deep learning framework.
Sci Rep
January 2025
School of Mechanical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
This paper introduces a novel method for spleen segmentation in ultrasound images, using a two-phase training approach. In the first phase, the SegFormerB0 network is trained to provide an initial segmentation. In the second phase, the network is further refined using the Pix2Pix structure, which enhances attention to details and corrects any erroneous or additional segments in the output.
View Article and Find Full Text PDFLongitudinal analysis of anthropometric measures over 5 years in patients with Friedreich ataxia in the EFACTS natural history study.
Eur J Neurol
January 2025
Department of Neurology, RWTH Aachen University, Aachen, Germany.
Background: Friedreich ataxia is a rare neurodegenerative disorder caused by frataxin deficiency. Both underweight and overweight occur in mitochondrial disorders, each with adverse health outcomes. We investigated the longitudinal evolution of anthropometric abnormalities in Friedreich ataxia and the hypothesis that both weight loss and weight gain are associated with faster disease progression.
View Article and Find Full Text PDFFatty Acids of European Sardine () White Muscle Can Discriminate Geographic Origin Along the Iberian Atlantic Coast.
Foods
January 2025
CESAM-Centre for Environmental and Marine Studies, Department of Chemistry, University of Aveiro, Santiago University Campus, 3810-193 Aveiro, Portugal.
The European sardine () ranks among the most valuable species of Iberian fisheries, and the accurate tracing of its geographic origin, once landed, is paramount to securing sustainable management of fishing stocks and discouraging fraudulent practices of illegal, unreported, and unregulated (IUU) fishing. The present study investigated the potential use of white muscle fatty acids (FAs) to successfully discriminate the geographic origin of samples obtained in seven commercially important fishing harbors along the Iberian Atlantic Coast. While 35 FAs were identified using gas chromatography-mass spectrometry in the white muscle of , the following, as determined by the Boruta algorithm, were key for sample discrimination: 14:0, 22:6-3, 22:5-3, 18:0, 20:5-3, 16:1-7, 16:0, and 18:1-7 (in increasing order of relevance).
View Article and Find Full Text PDFNeuroinflammatory Loop in Schizophrenia, Is There a Relationship with Symptoms or Cognition Decline?
Int J Mol Sci
January 2025
Departamento de Ciencias Biológicas y Químicas, Facultad De Medicina y Ciencia, Universidad San Sebastián, Sede Tres Pascualas Lientur 1457, Concepción 4080871, Chile.
Schizophrenia (SZ), a complex psychiatric disorder of neurodevelopment, is characterised by a range of symptoms, including hallucinations, delusions, social isolation and cognitive deterioration. One of the hypotheses that underlie SZ is related to inflammatory events which could be partly responsible for symptoms. However, it is unknown how inflammatory molecules can contribute to cognitive decline in SZ.
View Article and Find Full Text PDFIn Vitro Bioaccessibility of Edible Seaweed Proteins from the Chilean Coast and Proteins from the Novel Seaweed-Derived Mycoprotein.
Molecules
January 2025
Department of Chemical Engineering, Biotechnology, and Materials, Centre for Biotechnology and Bioengineering (CeBiB), University of Chile, Santiago 8330111, Chile.
Seaweed biomass is globally underutilized as a source of proteins despite its nutritional potential, with much of its use focused on hydrocolloid extraction. This study evaluated the nutritional quality and digestibility of protein and amino acids from two brown seaweeds ( spp. and ), one green seaweed ( spp.
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